Poly(amino acid)s have been extensively studied in biomedical applications

due to their excellent biocompatibility

biodegradability and various side groups for further functionalization. Poly (aspartic acid) can be synthesized by thermal polycondensation of L-aspartic acid

which is easily controlled and not costly. Its metabolites are non-toxic and would not produce toxic side effects to the surrounding tissue

liver

kidney

and red blood cells. It would be a good candidate for preparing polypeptide derivatives and was widely studied as the drug carriers

tissue engineering materials

etc. In this paper

research on poly(aspartic acid)s in the field of biomedical materials in recent years was reviewed

and mainly focused on the design and synthesis of poly (alpha

beta-L-aspartic acid) derivatives and their biomedical properties.