Research Progress in Hydrophilic Modified of Pharmaceutic Polymer Materials

Dian WANG; Hua-yue YIN; Chuan-hua LU

您当前的位置：

首页 >

文章列表页 >

Research Progress in Hydrophilic Modified of Pharmaceutic Polymer Materials

更新时间：2022-09-18

- Research Progress in Hydrophilic Modified of Pharmaceutic Polymer Materials
- Polymer Bulletin Vol. 26, Issue 2, Pages: 39-45(2013)
- 作者机构：
  
  安徽中医学院药学院，合肥　230031; 安徽省中药研究与开发重点实验室，合肥　230038
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2013-02，
  
  Received：30 July 2012，
  
  Revised：30 September 2012，
扫描看全文
Dian WANG, Hua-yue YIN, Chuan-hua LU. Research Progress in Hydrophilic Modified of Pharmaceutic Polymer Materials. [J]. Polymer Bulletin 26(2):39-45(2013)
DOI：

Dian WANG, Hua-yue YIN, Chuan-hua LU. Research Progress in Hydrophilic Modified of Pharmaceutic Polymer Materials. [J]. Polymer Bulletin 26(2):39-45(2013) DOI：

摘要

高分子材料在药物制剂和制药工艺上具有广泛的应用价值。新型制剂的研发与药用高分子材料的性能密切相关

特别是高分子胶束等两亲性高分子材料的使用尤为广泛

也是高分子材料当今研究的热点。本文着重对常见药用高分子材料亲水性修饰的亲水片段进行了概括总结。根据亲水片段的大小

分为小分子修饰、水溶性聚合物修饰以及水溶性高分子修饰三个部分

对药用高分子材料亲水修饰的修饰剂和修饰产物的性质特点、修饰方法以及其中的优势和不足尽可能的进行了综述

并对此进行了讨论和展望

以期能够给同行们提供参考并共讨论。

Abstract

Polymer materials has a wide range of application value in pharmaceutic preparation pharmaceutical processes.The research and development of new pharmaceutical manufacturing is intimately related to the property of pharmaceutic polymer materials

especially amphiphilic high molecular materials are widely used in the research and development of new pharmaceutical manufacturing and they are also the research hotspots

such as polymeric micelles.The common hydrophilic segments of amphiphilic pharmaceutic polymer materials are summarized in this paper

on the basis of size of hydrophilic segments

hydrophilic modification of pharmaceutic polymer materials is divided three classes——water-soluble micromolecules modified

water-soluble polymers modified and water-soluble high molecular materials modified.in order to give references to colleagues and discuss

the characteristics of the modifier and modified products and modification methods from the hydrophilic modification of pharmaceutic polymer materials and the advantages and disadvantages of modifier are reviewed as comprehensive as possible in this paper

at the same time

it is discussed and prospected.

关键词

药用高分子材料水溶性聚合物亲水性修饰胶束

Keywords

Pharmaceutic polymer materialsWater-soluble polymersHydrophilic modificationMicelles

references

更多指标>

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Self-assembly of Hyperbranched Polymer Micelles

Synthese of Temperature and pH Dual Responsive Nano Micelles Based on Poly (L-Glutamic Acid) and the Drug Release Profile

Advance of Drug-loaded Micelles Based on Amphiphilic Copolymer Self-assembly

Study of the Amphiphilic Block Copolymer Self-assembly and the Drug-loaded Micelles

Related Author

No data

Related Institution

College of Chemistry and Chemical Technology , Shanghai Jiao Tong University

The Key Laboratory of Food Colloids and Biotechnology,Ministry of Education, School of Chemical and Material Engineering,Jiangnan University

College of Chemical Engineering and Environment North University of China

School of Science North University of China

Institute of Fine Chemistry and Engineering, College of Chemistry and Chemical Engineering, Henan University

⁰