Research Progress in Zein as Drug Carrier

Wei ZHANG; Cai-yun ZHANG; Chuan-hua LU

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Research Progress in Zein as Drug Carrier

更新时间：2022-09-18

- Research Progress in Zein as Drug Carrier
- Polymer Bulletin Vol. 26, Issue 11, Pages: 49-53(2013)
- 作者机构：
  
  安徽中医药大学，合肥　230031；安徽省中药研究与开发重点实验室，合肥　230038
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2013-11，
  
  Received：06 March 2013，
  
  Revised：02 June 2013，
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Wei ZHANG, Cai-yun ZHANG, Chuan-hua LU. Research Progress in Zein as Drug Carrier. [J]. Polymer Bulletin 26(11):49-53(2013)
DOI：

Wei ZHANG, Cai-yun ZHANG, Chuan-hua LU. Research Progress in Zein as Drug Carrier. [J]. Polymer Bulletin 26(11):49-53(2013) DOI：

摘要

玉米醇溶蛋白是从玉米中分离提取的一种天然高分子蛋白

以其良好的生物相容性、生物可降解性、成膜性等而被广泛地应用于食品药品工业。近年来

玉米醇溶蛋白作为药物载体方面的研究引起了人们广泛的关注。本文对玉米醇溶蛋白的组成及其特性方面的研究进行了简要的综述并根据药物载体的不同形式

主要综述了玉米醇溶蛋白在片剂、微球(囊)、纳米纤维膜、原位凝胶及聚合物胶束等药物载体方面的应用情况

对其在药物载体中应用的优势和不足进行了详尽的综述

并对此进行了讨论和展望

以期待能够给同行们提供参考并供讨论。

Abstract

Zein is a kind of natural protein extracted from corn embryo. It has been widely used in food and pharmaceutical field based on its biocompatibility

biodegradability

and film-forming ability. In recent years

there are many studies on zein as drug carrier. In this paper

the research of composition and properties of the zein were briefly summarized

and the application of zein as drug carrier which including tablet

microspheres

nano-fibers

in situ gel and polymer micelle were mainly summarized according to the different forms of drug carrier. At the same time we have reviewed the advantages and disadvantages of zein as drug carrier which will provide reference to other colleagues.

关键词

玉米醇溶蛋白天然高分子材料药物载体

Keywords

ZeinNatural polymerDrug carrier

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