Preparation of Silk Fibroin/Collagen/Polymer Composite Fibers and its Mechanical Properties Study

Song-tao HUANG; Hong WANG; Zhong-rui ZHANG; Jia-kui WANG; Peng GAO; Li-hua YIN; Lin WANG; Zhan-hai YU

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Preparation of Silk Fibroin/Collagen/Polymer Composite Fibers and its Mechanical Properties Study

更新时间：2022-09-18

- Preparation of Silk Fibroin/Collagen/Polymer Composite Fibers and its Mechanical Properties Study
- Polymer Bulletin Vol. 27, Issue 6, Pages: 101-106(2014)
- 作者机构：
  
  兰州大学口腔医学院，兰州　730000
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2014-06，
  
  Received：02 August 2013，
  
  Revised：13 March 2014，
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Song-tao HUANG, Hong WANG, Zhong-rui ZHANG, Jia-kui WANG, Peng GAO, Li-hua YIN, Lin WANG, Zhan-hai YU. Preparation of Silk Fibroin/Collagen/Polymer Composite Fibers and its Mechanical Properties Study. [J]. Polymer Bulletin 27(6):101-106(2014)
DOI：

Song-tao HUANG, Hong WANG, Zhong-rui ZHANG, Jia-kui WANG, Peng GAO, Li-hua YIN, Lin WANG, Zhan-hai YU. Preparation of Silk Fibroin/Collagen/Polymer Composite Fibers and its Mechanical Properties Study. [J]. Polymer Bulletin 27(6):101-106(2014) DOI：

摘要

目前，将天然高分子蛋白和聚合物共混利用静电纺丝法制作各种组织工程支架材料倍受关注。基于这种研究背景，在本文中利用静电纺丝技术，制备了丝素(SF)/胶原(COL)/聚左旋乳酸(PLLA)和SF/COL/聚左旋乳酸-己内酯(PLCL)两种共混复合纤维膜，通过扫描电镜（SEM)对纤维形态结构分析，发现复合纤维形貌良好，直径较为均一。同时改变纺丝液中高分子蛋白的比例，复合纤维的直径也随之减小。此外，对复合纤维进行了力学性能测试，发现随着聚合物含量的增加，复合纤维膜的力学性能得以改善，SF/COL/PLCL组复合纤维的拉伸性能明显优于SF/COL/PLLA组。

Abstract

At present

the method which blends natural polymeric protein with polymer to fabricate a variety of materials for tissue engineering scaffolds through using electrospinning technique has attracted much attention. Based on this research background

in the paper

two new composite fibers from Silk fibroin (SF)/Collagen (COL)/poly-L-lactide (PLLA) and Silk Fibroin (SF)/Collagen (COL)/poly(L-actic-

-ε-caprolactone) (PLCL) are made by electrospinning. The surface morphologies of composite fibers can be observed by Scanning Electron Microscopy (SEM). The measured results show two new composite fibers have good morphologies and uniform diameters. At the same time

the observed results suggest that their diameter become more and more small while the ratio of the polymeric proteinis varied. Additionally

the mechanical measurements reveal that the mechanical properties improved with the increasing content of polymer in composite fiber membranes. As a result

the tensile properties of the SF/COL/PLCL composite fiber membranes were better than those of SF/COL/PLLA composite fiber membranes.

关键词

静电纺丝丝素胶原聚左旋乳酸聚左旋乳酸-己内酯力学性能

Keywords

ElectrospinningSFCOLPLLAPLCLMechanical properties

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