Preparation and Property of Antibacterial Plastic Modified with Novel Polymeric Quaternary Phosphonium Salts

Yuan LIU; Qiu-yuan ZENG; Tao QIU; Ning-jian AO

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Preparation and Property of Antibacterial Plastic Modified with Novel Polymeric Quaternary Phosphonium Salts

更新时间：2022-09-18

- Preparation and Property of Antibacterial Plastic Modified with Novel Polymeric Quaternary Phosphonium Salts
- Polymer Bulletin Vol. 27, Issue 7, Pages: 75-82(2014)
- 作者机构：
  
  1.暨南大学生物医学工程系，广州　510632
  2.中山大学工学院，广州　510006
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2014-07，
  
  Received：13 September 2013，
  
  Revised：20 January 2014，
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Yuan LIU, Qiu-yuan ZENG, Tao QIU, Ning-jian AO. Preparation and Property of Antibacterial Plastic Modified with Novel Polymeric Quaternary Phosphonium Salts. [J]. Polymer Bulletin 27(7):75-82(2014)
DOI：

Yuan LIU, Qiu-yuan ZENG, Tao QIU, Ning-jian AO. Preparation and Property of Antibacterial Plastic Modified with Novel Polymeric Quaternary Phosphonium Salts. [J]. Polymer Bulletin 27(7):75-82(2014) DOI：

摘要

高分子季鳞盐抗菌剂具有安全、高效的特点，使用过程中不会通过皮肤组织进行渗透。本文将实验室自制的新型高分子季鳞盐抗菌剂粉末与低密度聚乙烯(LDPE)基体材料共混，通过熔融挤出法制备了含梯度浓度抗菌剂的抗菌塑料，研究了不同抗菌剂添加浓度对基体材料熔融性质及其抗菌性能的影响，并探讨了抗菌塑料的生物安全性。结果表明，梯度浓度的抗菌剂改性塑料对金黄色葡萄球菌和大肠杆菌均有良好的抗菌效果；生物安全性测试结果表明，抗菌塑料的细胞毒性为0级，说明抗菌塑料具有较高的生物安全性。

Abstract

Antimicrobial polymeric quaternary phosphonium salt is characterized by safety and high efficiency. It will not penetrate into human body through skin and be invalidated by photolysis. Through molten extrusion

the concentration gradient of homemade novel antimicrobial polymeric quaternary phosphonium salt were mixed with the matrix material (low density polyethylene

LDPE)

and the antibacterial plastics were prepared. The influences of different antimicrobial concentration on the melting properties and antibacterial properties of the plastics were studied

and the biological safety of the plastics was discussed. It was indicated that the modified plastic with different concentration of antibacterial agent all have superior antibacterial activity against

. aureus and

. coli. Biosafety test illustrated that the cytotoxicity of the antibacterial plastics was 0 level and the plastics have high biosafety.

关键词

高分子季鳞盐抗菌塑料熔融指数抗菌性能细胞毒性

Keywords

Polymeric quaternary phosphonium saltAntibacterial plasticMelting propertiesAntibacterial propertiesCytotoxicity

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