Surface molecularly imprinted polymers (SMIPs) have attracted increasing research interest with potential applications such as chromatographic separations
solid phase extraction and chemo/biosensors in the last decade. The surface imprinting technology attempts to build molecular recognition systems on the supporting materials surface and enables template molecules to locate in the proximity or at the surface of the MIP. So compared to the conventional imprinted polymers
SMIPs exhibit more complete removal of templates
higher binding capacity
and faster binding kinetics. This short review discusses the recent progress in the field of surface molecularly imprinted technology and summarize the various supporting substrates employed to build molecular imprinted polymer with focus on the silicon material