Polyphosphazenes are hybrid inorganic-organic polymers composed of a backbone containing alternative phosphorus and nitrogen atoms with two (usually organic) side groups linked to each phosphorus atom. Various properties can be obtained due to the high flexibility in molecular design of polyphosphazene chemistry. Biocompatibility

biodegrability and functionalization are among the key factors in determining the applications of biodegradable polyphosphazenes in biomedical fields. In this paper

functional polyphosphazene-based biomaterials

including cationic polyphosphazene

photoluminiscent polyphosphazene

conducting polyphosphazene

and polyphosphazene-polyester copolymer etc.

were reviewed to introduce their recent developments. These functional polyphosphazenes can find wide applications in biomedical areas as tissue engineering scaffolds

drug and gene delivery carriers.