The chitosan solution and sodium hyaluronate solution was mixed to prepare the CS-SH polyelectrolyte composite (PECs) solution and characterized the size distribution and zeta potential of the colloidal particle formed in the solution. Then

removed the solvent with the technique freeze drying. The structure of PECs nanofibers mats was investigated by fourier transform infrared spectrometer (FT-IR). The morphology of PECs nanofiber mats was characterized by scanning electron microscope (SEM). Furthermore

the drug encapsulated and released properties of PECs nanofibrous membrane was studied by a hydrophobic drug paclitaxel (PTX). The results showed that the PECs nanofibers carrier demonstrated a slow released property for the PTX. As drug release carriers

it has played an important role in prolonging drug valid time

reducing the number of medicine

enhancing the treatment effect and reducing the toxicity.