Advance of Poly(lactic acid) Modified Chitosan in the Field of Biomedical

Xiao-li ZHANG; Xiang-mei WANG; Han-gen CHEN; Rui LIU

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Advance of Poly(lactic acid) Modified Chitosan in the Field of Biomedical

更新时间：2022-09-18

- Advance of Poly(lactic acid) Modified Chitosan in the Field of Biomedical
- Polymer Bulletin Vol. 26, Issue 11, Pages: 62-69(2013)
- 作者机构：
  
  1.中北大学理学院，太原　030051
  2.中北大学化工与环境学院，太原　030051
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2013-11，
  
  Received：22 April 2013，
  
  Revised：24 May 2013，
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Xiao-li ZHANG, Xiang-mei WANG, Han-gen CHEN, Rui LIU. Advance of Poly(lactic acid) Modified Chitosan in the Field of Biomedical. [J]. Polymer Bulletin 26(11):62-69(2013)
DOI：

Xiao-li ZHANG, Xiang-mei WANG, Han-gen CHEN, Rui LIU. Advance of Poly(lactic acid) Modified Chitosan in the Field of Biomedical. [J]. Polymer Bulletin 26(11):62-69(2013) DOI：

摘要

壳聚糖(CS)和聚乳酸(PLA)具有许多独特的性能

包括可生物降解性、良好的生物相容性

对人体无刺激、无毒

是一种绿色生物医药材料

具备潜在的应用价值。将二者单独用于医药领域优势不是很显著

而聚乳酸改性壳聚糖的产物及其衍生物能够很好地融合二者的优点

改性后能得到综合性能更好的生物医学复合材料。本文从聚乳酸改性壳聚糖的角度

综述了壳聚糖和聚乳酸的性质、改性原因、改性现状、改性产物的性能以及在医药领域的一些应用

重点介绍了改性产物在药物缓释方面的应用

并指出今后改性材料方面应注意的问题和发展趋势。

Abstract

Chitosan(CS) and poly(lactic acid)(PLA) were green biomedical materials with potential value for their unique properties including biodegradability

excellent biocompatibility

nonirritant

non-toxic. The advantage of applying separately them to the field of medicine was not significant

but the product of PLA modified CS and its derivatives had can be well consolidated the advantages of both

the better overall performance of the biomedical composite material can be obtained after modification. The property of CS and PLA

the modified reason and situation

application and properties of modified Chitosan in pharmaceutical field were summarized from the perspective of PLA modified CS

focuses on modification of product applications in drug delivery and pointed out the problems and develop tendency of modified materials.

关键词

壳聚糖聚乳酸改性药学材料

Keywords

ChitosanPoly(lactic acid)ModifiedPharmacyMaterial

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