Protein-based Multilayer Assembly : Fabrication and the Biomedical Application

Xue QU; Gang WU; Chang-sheng LIU

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Protein-based Multilayer Assembly : Fabrication and the Biomedical Application

更新时间：2022-09-18

- Protein-based Multilayer Assembly : Fabrication and the Biomedical Application
- Polymer Bulletin Vol. 27, Issue 10, Pages: 13-20(2014)
- 作者机构：
  
  1.华东理工大学超细材料教育部重点实验室，上海　200237
  2.华东理工大学生物反应器工程国家重点实验室，上海　200237
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2014-10，
  
  Received：23 June 2014，
  
  Revised：26 June 2014，
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Xue QU, Gang WU, Chang-sheng LIU. Protein-based Multilayer Assembly : Fabrication and the Biomedical Application. [J]. Polymer Bulletin 27(10):13-20(2014)
DOI：

Xue QU, Gang WU, Chang-sheng LIU. Protein-based Multilayer Assembly : Fabrication and the Biomedical Application. [J]. Polymer Bulletin 27(10):13-20(2014) DOI：

摘要

对蛋白质基自组装多层结构的发展和生物医学应用进行了综述。详细介绍了蛋白质多层结构的组装原理、组装基元类型、不同物理结构如涂层、微胶囊和纳米管的制备技术。阐述了蛋白质多层结构在抗凝血、抗菌、生物活性涂层、药物控释和生物分离方面的应用。最后对蛋白质基组装体系的优势进行总结，对其进一步的发展方向作了展望。

Abstract

This paper reviewed the development of protein-based multilayer assemblies. The assembling mechanisms

building blocks and physical morphologies such as coating

microcapsule and nanotubes of the protein assemblies were introduced in detail. Their biomedical applications such as antibacteriality

anticoagulation

bioactive coatings

controlled drug delivery and bioseparation were summarized as well. The advantages as well as the future developments of the protein multilayer assemblies were also addressed.

关键词

蛋白层层自组装生物医用功能

Keywords

ProteinLayer-by-Layer self assemblyBiomedical application

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School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology; Biomedical and Protective Materials Hubei Engineering Research Center

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