Research Status of the Surface Modification Method Based on Dopamine

De LIU; Yu-han LIU; Yan ZHANG; Pan CAO

doi:10.14028/j.cnki.1003-3726.2022.04.003

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Research Status of the Surface Modification Method Based on Dopamine

更新时间：2022-09-09

- Research Status of the Surface Modification Method Based on Dopamine
- Polymer Bulletin Vol. 35, Issue 4, Pages: 30-37(2022)
- 作者机构：
  
  扬州大学机械工程学院,扬州 225127
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2022.04.003
  CLC：
- Published：20 April 2022，
  
  Received：30 March 2021，
  
  Revised：12 August 2021，
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De LIU, Yu-han LIU, Yan ZHANG, Pan CAO. Research Status of the Surface Modification Method Based on Dopamine. [J]. Polymer Bulletin 35(4):30-37(2022)
DOI：

De LIU, Yu-han LIU, Yan ZHANG, Pan CAO. Research Status of the Surface Modification Method Based on Dopamine. [J]. Polymer Bulletin 35(4):30-37(2022) DOI： 10.14028/j.cnki.1003-3726.2022.04.003.

摘要

海洋贻贝类生物通过足丝分泌的黏附蛋白

在潮湿环境中可以短时间固化

并紧固黏附在基质表面。研究表明

4-二羟基-L-苯基丙氨酸(多巴

DOPA)是这种黏附蛋白中的重要组成部分。多巴胺(DA)作为DOPA的一种衍生物

拥有同样的强黏附性。且多巴胺的自聚合产物聚多巴胺(PDA)存在许多官能团

如邻苯二酚、胺、亚胺

这些官能团可以进一步用作材料的反应基团。基于这些优良的性质

多巴胺常被应用于材料的表面改性中。本文综述了多巴胺的聚合机理和黏附性质以及它们在生物材料领域、环境领域和医学领域等领域的应用现状

并提出多巴胺在表面改性的展望和现阶段存在的问题。

Abstract

Marine mussel-like organisms secrete adhesion proteins through foot filaments that can solidify for a short time in a humid environment and adhere tightly to the substrate surface. Studies have shown that 3

4-dihydroxy-Lphenylalanine (dopa

DOPA) is an important component of this adhesion protein. Dopamine (DA)

a derivative of DOPA

possessed the same strong adhesion properties. Moreover

the self-polymerization product of dopamine

polydopamine (PDA)

has many functional groups

such as catechol

amine

and imine

which can be further used as reactive groups in materials. Based on these excellent properties

dopamine is often applied in the surface modification of materials. In this paper

we reviewed the polymerization mechanism and adhesion properties of dopamine and their current applications in the fields of biomaterials

environment and medicine

and presented the prospect of dopamine in surface modification and the problems at the present stage.

关键词

黏附蛋白多巴胺黏附性表面改性

Keywords

Adhesion proteinDopamineAdherenceSurface modification

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Related Institution

School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology

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