最新刊期
卷 0 ， 期 0 ， 2020
- 摘要：Cyclodextrin-based nano-drug delivery systems include cyclodextrin-containing polymers, amphiphilic cyclodextrins, hydrophobic cyclodextrins and cyclodextrin-based supermolecular complexes. These nano-drug delivery systems can serve as multi-functional drug carriers, through the formation of inclusion complex or the form of cyclodextrin-drug conjugate. Moreover, they may significantly improve the physicochemical and biological properties of the free drug, enhance the therapeutic efficiency and reduce toxic side effects. This article reviews the recent research progress in cyclodextrin-based nano-drug delivery systems.关键词：Cyclodextrin;Inclusion complex;Drug-cyclodextrin conjugate;Drug delivery
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发布时间：2022-09-18 - 摘要：Polymer crystallization has always been a hotspot in the field of condensed matter research of polymer science. With supercritical fluids, especially supercritical CO2 (scCO2) used in polymer processing increasing, the polymer crystallization researches under the condition of scCO2 are even more important. High solubility in the polymer and good plasticizing effect, the properties as scCO2 has, can significantly reduce the glass transition temperature (Tg) and melting point (Tm), eventually changing the crystal form of the polymer and making the greater impact on crystallization dynamics. Thus the deep researches of polymer crystallization under conditions in scCO2 play an important role in guiding the practical application. In this paper, research progress of the form of chain, crystal morphology, blends characteristics and crystallization kinetics under scCO2 are reviewed.关键词：Supercritical carbon dioxide;Polymer crystallization;Crystalline morphology;Crystallization kinetics
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发布时间：2022-09-18 - 摘要：In recent years, hyperbranched polymers has drawn considerable attention in the chemistry, physics, materials, biology, and biomedicine fields for their unique properties not shared with conventional linear polymers, which can be attributed to their highly branched structures. Hyperbranched Polyimide (HBPI) is a new type of polymers based on hyperbranched macromolecules and polyimides, which has the specific three-dimensional molecular structure, highly branched molecular chains and many end-group functional groups on the surface of the molecular. Owing to these unique structural characters, excellent physical and chemical properties, and variety in synthesis and modification, HBPI has gave rise to their potential application in many fields. The application development of HBPI from 1999 when HBPI was first prepared until now in gas permeation membranes, proton exchange membranes, photosensitive and optical waveguide materials, fluorescence, dielectric materials, and composites is reviewed in this paper. The application mechanism in every field mentioned above is summarized, and the forecast to the future developments of the application of HBPI is also discussed.关键词：Hyperbranched polyimide;Application;Mechanism
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发布时间：2022-09-18 - 摘要：Polylactic acid (PLA) is at present one of the most promising biodegradable polymers and has a wide range of applications. It has become one of the most important biomedical materials. But the PLA also has many disadvantages, which limits its application in the medicine field. In this paper, the strong hydrophobicity, poor cellular affinity, poor mechanical properties, aseptic inflammation reaction resulted from local accumulation of lactic acid produced by degradation products, lacking series products whose repair, degradation and absorption speed cannot well matched their cell proliferation and tissue repair speed, high cost, poor hole forming performance of homopolymer are reviewed. Summarized the scheme at home and abroad in recent years in view of the above various defects made, and the direction of research and development of PLA medical modification are discussed.Besides, the improvements made in recent years for each of the above defects are summarized. At last, the research and development orientation on PLA medical modification are prospected.关键词：Poly(lactic acid);Biomedical materials;Modification
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发布时间：2022-09-18 - 摘要：Organic-inorganic nanocomposite microspheres are composite materials where two or more particles are dispersed on the nanometre scale through surface encapsulation or composite treatment. In recent years, organic-inorganic nanocomposite microspheres have attracted much attention due to their widely application prospects in various fields. In this review, the current mature synthesis technologies of organic-inorganic nanocomposite microspheres are summarized. The synthesis of organic-inorganic composite microspheres can be divided into three approaches: sol-gel, in situ polymerization, and other methods. The in situ polymerization method is introduced in details and the characteristic and application of different synthesis technique are analyzed and expounded. In addition, the potential applications of composite microspheres and future trends in the fields are also described.关键词：Nano materials;Organic-inorganic composite microspheres;Synthetic method;Research progress
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发布时间：2022-09-18 - 摘要：Zein is a kind of natural protein extracted from corn embryo. It has been widely used in food and pharmaceutical field based on its biocompatibility, biodegradability, and film-forming ability. In recent years, there are many studies on zein as drug carrier. In this paper, the research of composition and properties of the zein were briefly summarized,and the application of zein as drug carrier which including tablet, microspheres, nano-fibers, in situ gel and polymer micelle were mainly summarized according to the different forms of drug carrier. At the same time we have reviewed the advantages and disadvantages of zein as drug carrier which will provide reference to other colleagues.关键词：Zein;Natural polymer;Drug carrier
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发布时间：2022-09-18 - 摘要：Agricultural straw is one of the important renewable biomass resources. But it has not obtained sufficient attention and exploitation. With the strategy of sustainable development become a basic national strategy, using straw to produce environment-friendly and energy-saving materials have huge development potential. In this paper, we summarize the research progress in development of the straw composite materials in recent years based on a simple analysis of the straw’s species and composition, respectively, for several typical agricultural straws. The preparation of straw composite materials and the influence factors on the performance of the materials such as species and shapes were analyzed. Finally, the prospect of developing agricultural straw material industry was discussed.关键词：Agricultural straw;Composite materials;Renewable resources
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发布时间：2022-09-18 - 摘要：Chitosan(CS) and poly(lactic acid)(PLA) were green biomedical materials with potential value for their unique properties including biodegradability, excellent biocompatibility, nonirritant, non-toxic. The advantage of applying separately them to the field of medicine was not significant, but the product of PLA modified CS and its derivatives had can be well consolidated the advantages of both, the better overall performance of the biomedical composite material can be obtained after modification. The property of CS and PLA, the modified reason and situation, application and properties of modified Chitosan in pharmaceutical field were summarized from the perspective of PLA modified CS, focuses on modification of product applications in drug delivery and pointed out the problems and develop tendency of modified materials.关键词：Chitosan;Poly(lactic acid);Modified;Pharmacy;Material
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发布时间：2022-09-18 - 摘要：Sodium alginate is a natural biodegradable material, widely used in the medical field because of its good biocompatibility, film-forming, moisture absorption and ion-crosslinked gel properties. Preparation of sodium alginate composite nanofibers is helpful to improve the properties and expand the applications of sodium alginate. This paper introduces the development of sodium alginate composite nanofibers preparation by electrospinning in recent years at home and abroad, focusing on research and application of the SA/PEO, SA/PVA, SA/Glycerol, SA/gelatin and SA/Chitosan composite nanofibers in the fields of wound dressings, tissue engineering scaffolds, drug release systems. The potential applications and prospect of sodium alginate nanofibers have also been described.关键词：Electrospinning;Sodium alginate;Nanofibers;Composite
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发布时间：2022-09-18 - 摘要：Polyfluorene PFketal with ketal-containing side chain was synthesized by Suzuki polymerization,acid treatment of PFketal resulted in polymer PFOH which consists hydroxyl groups. The polymers were characterized by FT-IR, 1H-NMR, GPC, UV-Vis, PL and cyclic voltammogram(CV) measurements. Two polymers exhibit similar spectral properties, they both show maximum UV absorption peaks at 387 nm and maximum photoluminescence peaks at 424 nm. CV spectra indicate that PFOH shows relatively lower oxidation onset potential compared with PFketal. The solubility of polymers in polar solvents can be improved by incorporation of hydroxyl groups, PFOH is readily soluble in N,N-Dimethylformamide (DMF) and Dimethyl sulfoxide (DMSO), which are poor solvents for PFketal.关键词：Polyfluorene;Suzuki polymerization;2, 7-Dibromo-9, 9-bis(2, 2-dimethyl-1, 3-dioxolan-4-yl)-fluorene
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发布时间：2022-09-18 - 摘要：Chitosan graft acrylic acid and acrylamide superabsorbents(CPAAM) are prepared by solution polymerization and soaked in ethanol-NaOH solution using chitosan, acrylic acid(AA) and acrylamide(AM) as raw materials(monomers), potassium peroxydisulfate(KPS) as initiator, N,N’-methylene-bis-acrylamide(NMBA) as crosslinker, and the absorbencies in multiple component salt-mixing solutions are measured. The results have shown that the equilibrium absorbencies of the CPAAM decrease rapidly with increasing the concentration; the effect of the non-electrolyte solutions on the absorbency is little while the effect of the electrolyte solutions on it is large. The cation valence of the electrolyte solutions significantly affects the absorbency of the CPAAM; in the same concentration of solution, the effect of high valence cations is greater than that of the monovalent cations for the absorbency of CPAAM. These are agreeable with the results of the absorbencies in single salt solutions for high water-absorbing resins. The order of the absorbencies in binary NH4+/Ca2+ salt-mixing solutions for CPAAM is NH4HCO3/CaCl2> (NH4)3PO4/CaCl2>NH4Cl/CaCl2 while that in ternary K+/NH4+/urea salt-mixing solutions for CPAAM is KCl/NH4HCO3/CO(NH2)2>KCl/(NH4)3PO4/CO(NH2)2, and that in quaternary K+/NH4+/urea salt-mixing solutions is (NH4)3PO4/KCl/MgCl2/CO(NH2)2>(NH4)3PO4/KCl/CaCl2/CO(NH2)2. The suitable water temperatures for the maximum absorbencies in the salt-mixing solutions for CPAAM are all about 25℃.关键词：Superabsorbent;High water-absorbing resin;Chitosan;Acrylamide;Acrylic acid;Absorbency;Salt-mixing solution
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发布时间：2022-09-18 - 摘要：The treatment of simulation wastewater containing partially hydrolyzed polyacrylamide (HPAM) by Fenton’s reagent (a mixture of H2O2 and Fe2+) oxidation processes was carried out in a batch reactor. The effect of operating conditions such as the concentration of H2O2, the concentration of Fe2+, temperature, reaction time and pH value on the efficiency of Fenton oxidation processes had been optimized. It was demonstrated that Fenton’s reagent can effectively oxidate simulation HPAM wastewater. The results showed that the removal rate of HPAM and CODCr were 87.61% and 82.60%, respectively, under the optimum conditions of H2O2 5.3mmol/L, Fe2+ 1.44mmol/L, temperature 30℃, reaction time 15min, pH value from 3 to 4. The FTIR spectrum indicated that the amide group of HPAM was oxidized into carboxyl group.关键词：Fenton’s reagent;Oxidation treatment;Polyacrylamide;Wastewater
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发布时间：2022-09-18 - 摘要：With allyl alcohol polyoxyethylene ether (APEG) and maleic anhydride (MA) as the monomer, K2S2O8 as the initiator, distilled water as the solven, synthesis of P(APEG-co-MA) by free radical polymerization under the 65℃. Using gel permeation chromatograph measurement allyl alcohol polyethylene glycol ether and maleic anhydride copolymer composition, then use F-R method, K-T method and YBR method for the calculation of the reactivity ratio by experimental data. The results showed that, allyl alcohol polyethylene glycol ether and maleic anhydride reactivity ratio respectively are r1=0.33090, r2=0.04761 under the condition of the low conversion rate. Compared with maleic anhydride, allyl alcohol polyoxyethylene is more likely to tend to gather, and the poly maleic anhydride basic will not occur.关键词：PEG;MA;Reactivity ratio;GPC
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发布时间：2022-09-18 - 摘要：PEG-g-chitosan nanoparticles are promising drug vehicles for anti-tumor drug, DNA and peptide, etc. PEG-grafted chitosan can improve the solubility of chitosan in aqueous solutions or organic solvents, have the ability to avoid reticuloendothelial system (RES) of liver and prolonged blood circulation time, in order to deliver more drugs to the targeting area. Now,PEG-grafted chitosan play an important roles in the field of biological medicines. This article reviewed recent key advancements of PEG-grafted chitosan nanoparticles and discussed the factors which would improve its drug therapeutic effect, including its tumor-targeting and controlled release ability, etc.关键词：PEG;Chitosan;Drug vehicles
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发布时间：2022-09-18 - 摘要：As science, the research is indispensable for teaching course as well. The results in teaching research should be exhibited in understanding course content deeply, in textbook edited newly and teaching practices. Besides, the results in teaching research should be write a paper to publish in journal openly. It is the published paper that can be seen by the craft brother in the universities and will be in favor of all readers. It is more important to create good environment of teaching research in the country and discuss various point of view each other.关键词：Teaching research;Polymer;Polymer physics;Relationship between structure and properties
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发布时间：2022-09-18 - 摘要：Several concepts concerned with molecular weight regulator were introduced, including chain-transfer agent, molecular weight stabilizer, viscosity stabilizer and end capping agent. Their connections, similarities and differences with molecular weight regulator and applications were summarized detailly in the addition polymerization and condensation polymerization. In the addition polymerization, the molecular weight regulator and chain-transfer agent are the same concept. Whileas in the condensation polymerization, there are several concepts concerned with with molecular weight regulator. There is no uniform definition. It was always called viscosity stabilizer because the relationship between the molecular weight and viscosity is very intimate. And it was pointed out that synthetically using the knowledge of polymer physics and polymer chemistry was very important when teaching the polymer physics or polymer chemistry.关键词：Molecular weight regulator;Chain-transfer agent;Molecular weight stabilizer;Viscosity stabilizer;End capping agent
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发布时间：2022-09-18
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