Porogen leaching method is most commonly used for fabricating micro- and macro-porous polymer scaffolds. The advantage of this method is that the process is easy to carry out and easy to control the pore size and porosity by selecting suitable particle size and amount of the added salt particles. However

most of the scaffolds prepared by this method are limited to two-dimensional films with 2~3mm

and the scaffolds usually have a poor interconnectivity between macropores. Moreover

the porogen and solvent can remain in polymer scaffolds. The development situation of modified porogen leaching method is reviewed in this paper

and the effects and deficiencies of the modification are discussed.