PEG-g-chitosan nanoparticles are promising drug vehicles for anti-tumor drug

DNA and peptide

etc. PEG-grafted chitosan can improve the solubility of chitosan in aqueous solutions or organic solvents

have the ability to avoid reticuloendothelial system (RES) of liver and prolonged blood circulation time

in order to deliver more drugs to the targeting area. Now

PEG-grafted chitosan play an important roles in the field of biological medicines. This article reviewed recent key advancements of PEG-grafted chitosan nanoparticles and discussed the factors which would improve its drug therapeutic effect

including its tumor-targeting and controlled release ability

etc.