3D printing

also named as Additive Manufacturing

is attracting increasing attentions from tissue engineering

aerospace engineering

automotive industry and electronics

due to its advantages of free form design and manufacturing. Besides the complex structures and excellent biomedical properties

surface performances of 3D printing skeleton and organs are also crucial for practical applications

for example

biocompatible

antibacterial and cell adhesion properties are necessary to 3D printed tissue scaffolds and organs. Therefore

combining 3D printing technology with traditional surface modifications is significant for expanding 3D printing’s applications. Multifunctional 3D printed skeleton and organs can be offered by post surface biochemistry modification of the skeleton and organs with retaining their bulk properties

and a more splendid application can be expected. In this review

we summarized the recent progress in the 3D printing biomedical materials based on the surface modification of 3D printed skeleton and organs.