Polyisobutylene has a good biocompatibility due to its fully saturated structure and the presence of only carbon-hydrogen bonds. Polyisobutylene-based bioinert elastomers have made many advances in recent years
including PIB-poly(methyl methacrylate) (PMMA) for toughening of bone cements; PIB-cyanoacrylate (CA) for intervertebral disk replacement; PIB-based amphipathic networks(APNs) for immunoisolatory membranes and the development of polyisobutylene based polyurethanes(PU) and polyureas. Significant advances have also been made in poly(styrene-
b
-isobutylene-
b
-styrene) biomedical materials
including SIBS for drug delivery vehicles
glaucoma diversion tubes
heart valves
and artificial blood vessels. It also looks forward to the future development of polyisobutylene-based bioinert elastomers.