Sulfobetaine methacrylate (SBMA) is copolymerized with 2

3-dihydroxypropyl methacrylate (GMMA) in the presence of boric acid as crosslinking agent. The prepared material exhibits multi-stimuli responsive shape memory behaviors: it can rapidly recover to its initial shape upon heating

absorbing and moisture in humid environments. The shape memory effect can be well adjusted via incorporation of sodium chloride to induce the dissociation of electrostatic interactions between PSBMA chains

leading to reduced transition temperature and faster shape recovery rate. The dynamic nature of boron ester bonds and electrostatic interaction endows the material with effective and rapid self-healing ability. We also demonstrate the deployment process of the dressing that a sample with an initially circular shape can perfectly fit and tightly bound to the wound site after moisture-induced shape recovery. The proposed zwitterionic polymer can possibly extend the application scope of shape memory polymers and pave a new way for the design of wound dressings.