基于聚(<italic style="font-style: italic">N,N</italic>-二乙基丙烯酰胺)温度响应型接枝共聚物的制备与表征

边智宇; 张芳; 孟祥红; 刘炳杰

doi:10.14028/j.cnki.1003-3726.2024.24.174

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基于聚(N,N-二乙基丙烯酰胺)温度响应型接枝共聚物的制备与表征

研究论文 | 更新时间：2024-11-20

- 基于聚(N,N-二乙基丙烯酰胺)温度响应型接枝共聚物的制备与表征
- Preparation and Characterization of Temperature Responsive Graft Copolymer Based on Poly(N,N-diethylacrylamide)
- 高分子通报 2024年37卷第11期页码：1597-1607
- 作者机构：
  
  中国海洋大学食品科学与工程学院，青岛 266404
- 作者简介：
  
  *刘炳杰，E-mail: liubj@ouc.edu.cn
- 基金信息：
  
  国家重点研发计划(2021YFD2100501)
- DOI：10.14028/j.cnki.1003-3726.2024.24.174
  中图分类号：
- 纸质出版日期：2024-11-20，
  
  网络出版日期：2024-09-05，
  
  收稿日期：2024-06-12，
  
  录用日期：2024-07-23
- 稿件说明：
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边智宇, 张芳, 孟祥红, 刘炳杰. 基于聚(N,N-二乙基丙烯酰胺)温度响应型接枝共聚物的制备与表征. 高分子通报, 2024, 37(11), 1597–1607

Bian, Z. Y.; Zhang, F.; Meng, X. H.; Liu, B. J. Preparation and characterization of temperature responsive graft copolymer based on poly(N,N-diethylacrylamide). Polym. Bull. (in Chinese), 2024, 37(11), 1597–1607
边智宇, 张芳, 孟祥红, 刘炳杰. 基于聚(N,N-二乙基丙烯酰胺)温度响应型接枝共聚物的制备与表征. 高分子通报, 2024, 37(11), 1597–1607 DOI： 10.14028/j.cnki.1003-3726.2024.24.174.

Bian, Z. Y.; Zhang, F.; Meng, X. H.; Liu, B. J. Preparation and characterization of temperature responsive graft copolymer based on poly(N,N-diethylacrylamide). Polym. Bull. (in Chinese), 2024, 37(11), 1597–1607 DOI： 10.14028/j.cnki.1003-3726.2024.24.174.

摘要

以明胶和

-二乙基丙烯酰胺(DEAM)为原料，通过自由基共聚反应，成功合成了具有温度响应性的接枝共聚物明胶-

-聚(

-二乙基丙烯酰胺)(GPD)。利用傅里叶变换红外光谱(FTIR)、纳米粒度分析仪、分光光度法、光学显微镜、扫描电子显微镜(SEM)、旋转流变仪和细胞毒性试验对GPD进行表征和分析。结果表明，当DEAM的用量为0.25 mL时，合成的GPD具有快速且可逆的温度响应性，测得的相转变温度(LCST)为29.5 ℃。随着温度升至LCST以上，GPD水溶液会由无色透明变为白色不透明。进一步探究发现，在临近LCST时，小的温度变化便会引起溶液体系中GPD与水分子之间亲-疏水相互作用的改变，进而引发GPD分子链重排，出现“水合-脱水”现象，即发生相转变。

Abstract

Gelatin-

-poly(

-diethylacrylamide) copolymer (GPD)

the temperature responsive graft copolymer

was

successfully synthesized by free radical copolymerization reaction using gelatin and

-diethylacrylamide (DEAM) as raw materials. Fourier transform infrared spectroscopy (FTIR)

nanoparticle size analyzer

spectrophotometry

optical microscopy

scanning electron microscopy (SEM)

rotational rheometer

and cytotoxicity test were used to characterize and analyze GPD. The results showed that GPD has been found to respond to temperature change quickly and reversibly

with a measured lower critical solution temperature (LCST) of 29.5 ℃ when the amount of DEAM was 0.25 mL. As the temperature rose above LCST

the GPD aqueous solution turned from colorless and transparent to white and opaque. Further investigation revealed that a slight temperature change near the LCST could alter the hydrophilic-hydrophobic interactions between GPD and water molecules in the solution system. The rearrangement of the GPD molecular chains led to the “hydration-dehydration” phenomenon

also known as the phase transition.

关键词

明胶NN-二乙基丙烯酰胺纳米凝胶温度响应性相转变

Keywords

GelatinNN-diethylacrylamideNanogelTemperature responsivenessPhase transition

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Preparation and Characterization of Temperature Responsive Graft Copolymer Based on Poly(N,N-diethylacrylamide)

DOI：10.14028/j.cnki.1003-3726.2024.24.174

摘要

Abstract

关键词

Keywords

references