功能性聚合物微球的沉淀聚合制备技术形貌调控研究进展

张瑜菲; 常添笑; 石行波; 蔡玉东; 陈商涛; 杜滨阳

doi:10.14028/j.cnki.1003-3726.2025.25.272

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功能性聚合物微球的沉淀聚合制备技术形貌调控研究进展

综述 | 更新时间：2026-03-02

- 功能性聚合物微球的沉淀聚合制备技术形貌调控研究进展
- Research Progress on Precipitation Polymerization and Morphology Regulation of Functional Polymer Microspheres
- 高分子通报 2026年39卷第3期页码：388-404
- 作者机构：
  
  浙江大学工程师学院　杭州　 310015
  中国石油天然气股份有限公司石油化工研究院　北京　 102206
- 作者简介：
  
  changtianxiao@petrochina.com.cn
  chenst7890@petrochina.com.cn
  duby@zju.edu.cn
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2025.25.272
  中图分类号：
- 收稿：2025-09-11，
  
  录用：2025-10-27，
  
  网络首发：2025-12-17，
  
  纸质出版：2026-03-20
- 稿件说明：
移动端阅览
张瑜菲, 常添笑, 石行波, 蔡玉东, 陈商涛, 杜滨阳. 功能性聚合物微球的沉淀聚合制备技术形貌调控研究进展. 高分子通报, 2026, 39(3), 388-404.

Zhang, Y. F.; Chang, T. X.; Shi, X. B.; Cai, Y. D.; Chen, S. T.; Du, B. Y. Research progress on precipitation polymerization and morphology regulation of functional polymer microspheres. Polym. Bull. (in Chinese), 2026, 39(3), 388-404.
张瑜菲, 常添笑, 石行波, 蔡玉东, 陈商涛, 杜滨阳. 功能性聚合物微球的沉淀聚合制备技术形貌调控研究进展. 高分子通报, 2026, 39(3), 388-404. DOI： 10.14028/j.cnki.1003-3726.2025.25.272.

Zhang, Y. F.; Chang, T. X.; Shi, X. B.; Cai, Y. D.; Chen, S. T.; Du, B. Y. Research progress on precipitation polymerization and morphology regulation of functional polymer microspheres. Polym. Bull. (in Chinese), 2026, 39(3), 388-404. DOI： 10.14028/j.cnki.1003-3726.2025.25.272.

摘要

功能性聚合物微球因其独特的微观形貌和优异的性能，在生物医学、化工、电子信息、环境等领域具有广阔的应用前景。沉淀聚合作为制备功能性聚合物微球的核心技术之一，相较于其他制备方法，因其具有产物纯度高、粒径可控且无需外加添加剂等优势而备受关注。本文综述了不同类型沉淀聚合(如传统沉淀聚合、蒸馏/回流沉淀聚合、光引发沉淀聚合、可控/“活性”自由基沉淀聚合、自稳定沉淀聚合)的工艺特点及应用场景，并结合沉淀聚合的三大典型机理，探讨了温度、单体浓度、搅拌速率、溶剂性质、交联剂等关键参数对微球形貌的调控规律，为功能性微球的可控制备与高端化应用提供理论、实验参考以及研究思路。

Abstract

Functional polymer microspheres

known for their well-controlled morphology and unique functions

have broad applications in biomedicine

chemical engineering

electronic information

and environmental protection. Precipitation polymerization is a key technology for preparing functional polymer microspheres and stands out among other conventional methods because of its distinct advantages

such as high product purity

controllable particle size

and the absence of additives. This review summarizes the characteristics and applications of various types of precipitation polymerization (including conventional precipitation polymerization

distillation/reflux precipitation polymerization

controlled/“living” radical precipitation polymerization

and self-stabilized precipitation polymerization) and discusses the influence of key parameters

such as temperature

monomer concentration

stirring rate

solvent

and crosslinking agent

on the morphologies and properties of the resulting microspheres based on the three typical mechanisms of precipitation. This review provides theoretical and experimental references for the controlled preparation of functional microspheres and highlights promising research directions for their high-end applications.

关键词

Keywords

references

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