Applications of Biomaterial Polyamidoamine Dendrimers in Medicine

Ling YE; Wei GU; Yu-lan ZHOU

doi:10.14028/j.cnki.1003-3726.2002.04.001

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Applications of Biomaterial Polyamidoamine Dendrimers in Medicine

更新时间：2022-09-18

- Applications of Biomaterial Polyamidoamine Dendrimers in Medicine
- Polymer Bulletin Vol. 15, Issue 4, Pages: 1-5(2002)
- 作者机构：
  
  首都医科大学化学教研室，北京　100054
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2002.04.001
  CLC：
- Published：2002-08，
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Ling YE, Wei GU, Yu-lan ZHOU. Applications of Biomaterial Polyamidoamine Dendrimers in Medicine. [J]. Polymer Bulletin 15(4):1-5(2002)
DOI：

Ling YE, Wei GU, Yu-lan ZHOU. Applications of Biomaterial Polyamidoamine Dendrimers in Medicine. [J]. Polymer Bulletin 15(4):1-5(2002) DOI： 10.14028/j.cnki.1003-3726.2002.04.001.

摘要

聚酰胺-胺(PAMAM) 树状大分子是一类新型纳米生物材料

这类分子可通过有机合成的方法精确控制分子的结构和相对分子质量。其独特的分子结构使之在许多领域获得广泛应用。本文着重介绍了PAMAM 树状大分子作为基因载体、药物载体、磁共振造影剂和硼中子俘获治疗试剂等在医学领域中的研究进展。

Abstract

Polyamidoamine(PAMAM) dendrimers are a class of new nanoscale dendritic macromolecules

they are synthesized by reiterative Michale addition and amidation reactions.Their structure and molecular weight can be accurately controlled.Therefore

these unique features have made their potential applications in many areas.This review is emphasis on PAMAM dendrimers' advances in applications especially in medicine such as gene carriers

drug delivery

MRI and BNCT.

关键词

聚酰胺-胺树状大分子药物载体

Keywords

PolyamidoamineDendrimersDrug delivery

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Beijing laboratory of biological materials, Beijing University of Chemical Technology

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Beijing JiShuiTan Hospital, the Fourth Clinical Medical College of Peking University

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Key Laboratory of Rubber-plastics of Ministry of Education/Shandong Provincial Key Laboratory of Rubber-plastics , Qingdao University of Science & Technology

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