Advances in Amphiphilic Polymers Containing Cholesterol/Bile Acids

Qing-guo XU; Xu-bo YUAN; Jin CHANG

doi:10.14028/j.cnki.1003-3726.2004.03.011

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Advances in Amphiphilic Polymers Containing Cholesterol/Bile Acids

更新时间：2022-09-18

- Advances in Amphiphilic Polymers Containing Cholesterol/Bile Acids
- Polymer Bulletin Vol. 17, Issue 3, Pages: 76-83(2004)
- 作者机构：
  
  天津大学材料学院生物纳米技术研究所，天津　300072
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2004.03.011
  CLC：
- Published：2004-06，
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Qing-guo XU, Xu-bo YUAN, Jin CHANG. Advances in Amphiphilic Polymers Containing Cholesterol/Bile Acids. [J]. Polymer Bulletin 17(3):76-83(2004)
DOI：

Qing-guo XU, Xu-bo YUAN, Jin CHANG. Advances in Amphiphilic Polymers Containing Cholesterol/Bile Acids. [J]. Polymer Bulletin 17(3):76-83(2004) DOI： 10.14028/j.cnki.1003-3726.2004.03.011.

摘要

胆固醇和胆汁酸是广泛存在于自然界中的天然物质，生物相容性好，被广泛地用于高分子的疏水性改性，得到的双亲性聚合物，在水相中可以自组装或自聚集成纳米粒子。本文综述了含胆固醇或胆汁酸的双亲性聚合物的最新研究进展以及它们在药物载体系统中的应用。

Abstract

Cholesterol and bile acids extensively exist in nature

and they are biocompatible.Polymers are hydrophobized with cholesterol and bile acids to get amphiphilic polymers

which have potentials to self-assemble into polymeric micelles.The objective of this review is to summarize the recent advances in unveiling selfassembly behavior of the amphiphilic polymers containing cholesterol or bile acids and their applications in drug delivery systems.

关键词

胆固醇胆汁酸双亲性聚合物聚合物胶束药物载体系统

Keywords

CholesterolBile acidsAmphiphilic polymerPolymeric micellesDrug delivery systems

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