Applications of Cyclodextrin Polymer in the Pharmic Research

Ning LI; Yun-hui ZHANG; Xiao-li XIONG

doi:10.14028/j.cnki.1003-3726.2005.06.001

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Applications of Cyclodextrin Polymer in the Pharmic Research

更新时间：2022-09-18

- Applications of Cyclodextrin Polymer in the Pharmic Research
- Polymer Bulletin Vol. 18, Issue 6, Pages: 1-6(2005)
- 作者机构：
  
  1.天津大学药物科学与技术学院，天津　300072
  2.重庆佳通有限公司，重庆　400052
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2005.06.001
  CLC：
- Published：2005-12，
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Ning LI, Yun-hui ZHANG, Xiao-li XIONG. Applications of Cyclodextrin Polymer in the Pharmic Research. [J]. Polymer Bulletin 18(6):1-6(2005)
DOI：

Ning LI, Yun-hui ZHANG, Xiao-li XIONG. Applications of Cyclodextrin Polymer in the Pharmic Research. [J]. Polymer Bulletin 18(6):1-6(2005) DOI： 10.14028/j.cnki.1003-3726.2005.06.001.

摘要

环糊精聚合物既保持了环糊精包结、缓控释、催化和识别的能力，又兼具高聚物良好的机械强度、较好的稳定性和化学可调性，是一类很有潜力的功能高分子材料，引起了越来越多的关注。本文在概述了国内外关于环糊精高分子的类型及合成方法的基础上，重点综述了环糊精高聚物在药物的手性分离、分子印迹技术、给药系统以及在提高药物溶解度等方面的最新的研究进展。

Abstract

Cyclodextrin polymers (CDPs) not only have the inclusion ability

the controlled release ability

the catalysis ability and the selective ability

like their parent CDs

but also have fine mechanical intensity and the excellent stability.In addition

they exhibit various physical properties that have been impossible to obtain with their parent CDs.These lead CDPs to much attention.In this paper

progress in the preparation methods and the types of CDPs was summarized and application of CDPs in the enantiomer separation of chiral pharmaceuticals

improvement of the drug release

increase of the drug solubility

molecular imprinting technique and the drug delivery system was reviewed.

关键词

环糊精聚合物手性分离分子印迹聚合物药物释放给药系统

Keywords

Cyclodextrin polymers (CDPs)Enantiomer separationMolecular imprinted polymerDrug releaseDrug delivery system

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College of Chemical Engineering and Machinery, Eastern Liaoning University

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