The Research and Development of Novel-style Drug Delivery Systems from Alginate

Hong-bing LI

doi:10.14028/j.cnki.1003-3726.2006.08.006

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The Research and Development of Novel-style Drug Delivery Systems from Alginate

更新时间：2022-09-18

- The Research and Development of Novel-style Drug Delivery Systems from Alginate
- Polymer Bulletin Vol. 19, Issue 8, Pages: 39-43,69(2006)
- 作者机构：
  
  天津大学化工学院，天津　300072
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2006.08.006
  CLC：
- Published：2006-08，
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Hong-bing LI. The Research and Development of Novel-style Drug Delivery Systems from Alginate. [J]. Polymer Bulletin 19(8):39-43,69(2006)
DOI：

Hong-bing LI. The Research and Development of Novel-style Drug Delivery Systems from Alginate. [J]. Polymer Bulletin 19(8):39-43,69(2006) DOI： 10.14028/j.cnki.1003-3726.2006.08.006.

摘要

海藻酸（Alginate 或ALG）的药理学基础和在药物上的实际应用证明

海藻酸具有良好的生物相容性

由于在温和条件下与二价阳离子形成凝胶等独特的物理化学性能

用它作为缓释包衣、结肠给药、微球栓塞、纳米给药、基因治疗、眼部给药、外科修复材料和透皮给药等新剂型药物转运载体

可使药物疗效提高

毒副作用减小

用药更方便。本文综述了国内海藻酸产品的现状

阐述了海藻酸的开发前景。

Abstract

The pharmacology of alginate and the practical usage of alginate as medicines

confirmed that alginate has better biocompliance. As well as its special physicochemical properties

such as forming gels with divalent cations under mild conditions

its services as delivery carrier for released coating

colon target system

microspheric embolus

nano-particle medicine

gene cure

ophthalmic drug delivery system

surgery recovering materials and transdermal therapeutic systems

increase the bioavailability of the drugs

and thus its therapeutic effect

reduce side effects

contribute to improve patient compliance. The article treats of the actuality of alginate product in china and expounds the promising perspective of alginate development.

关键词

海藻酸生物相容性药物转运载体凝胶

Keywords

AlginateBiocomplianceDrug delivery carrierGel

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Related Institution

Key Laboratory of Eco-functional Polymer Materials of the Ministry of Education, Key Laboratory of Eco-environmental Polymer Materials of Gansu Province, College of Chemistry & Chemical Engineering, Northwest Normal University

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