Progress on Layer-by-Layer Self-assemble Technique in Surface Design of Biomaterials

Quan-kui LIN; Jian JI; Qing-gang TAN; Ke-feng REN; Jia-cong SHEN

doi:10.14028/j.cnki.1003-3726.2006.08.009

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Progress on Layer-by-Layer Self-assemble Technique in Surface Design of Biomaterials

更新时间：2022-09-18

- Progress on Layer-by-Layer Self-assemble Technique in Surface Design of Biomaterials
- Polymer Bulletin Vol. 19, Issue 8, Pages: 58-63(2006)
- 作者机构：
  
  浙江大学高分子科学与工程学系，杭州　310027
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2006.08.009
  CLC：
- Published：2006-08，
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Quan-kui LIN, Jian JI, Qing-gang TAN, Ke-feng REN, Jia-cong SHEN. Progress on Layer-by-Layer Self-assemble Technique in Surface Design of Biomaterials. [J]. Polymer Bulletin 19(8):58-63(2006)
DOI：

Quan-kui LIN, Jian JI, Qing-gang TAN, Ke-feng REN, Jia-cong SHEN. Progress on Layer-by-Layer Self-assemble Technique in Surface Design of Biomaterials. [J]. Polymer Bulletin 19(8):58-63(2006) DOI： 10.14028/j.cnki.1003-3726.2006.08.009.

摘要

基于聚电解质阴阳离子交替组装的层层自组装技术由于可在温和的条件下实现多种生物大分子在材料表面的固定

并通过对组装条件的控制实现多种生物功能

已成为生物医用材料表面设计的重要手段。本文对层层自组装技术在构建血液相容性界面、组织工程表面、药物控释涂层等生物医用材料领域的应用研究进行了比较系统的阐述。

Abstract

The Layer-by-Layer self-assembly (LbL)of polycations and polyanions into multilayers has emerged as an efficient

versatile

yet simple

technique to create biologically active surfaces .By controlling the assemble condition

bioactive molecules

such as drugs

enzymes

DNA

or proteins

may be incorporated in the multilayer during the polyelecrolyte deposition process .The LbL technique has been recognized as an important means in designing the surfaces of the biomaterials .This paper summarized the progress on the Layer-by-Layer self-assemble technique in the design of the biointerface for cardiovascular device

tissue engineering scaffold

drug delivery systems

and so on .

关键词

层层自组装技术血液相容性细胞相容性药物控释抗菌

Keywords

Layer-by-LayerBlood compatibilityCell compatibilityDrug deliveryAntibacterial

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Xi’an Key Laboratory of Advanced Performance Materials and Polymers, Shaanxi University of Science and Technology

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