Gene delivery system is indispensable for gene therapy .Recently

research on polymeric gene delivery vectors aims at developing non low cytotoxic cationic polymers for safe and efficient gene transfer .As a family of natural compounds

carbohydrate-based cationic polymer vectors are widely studied and applied to gene delivery due to their good biocompatibility and low cytotoxicity .This review describes the mechanism of polymeric gene delivery processes .Also

the latest typical carbohydrate-based polymers as non-viral vectors are reviewed .