Preparation and Characterization of Quantum Dots-tagged Self-assembly Nanoparticles

Yong YANG; Xiao-qing DONG; Lei ZHANG; Jin CHANG

doi:10.14028/j.cnki.1003-3726.2007.06.006

您当前的位置：

首页 >

文章列表页 >

Preparation and Characterization of Quantum Dots-tagged Self-assembly Nanoparticles

更新时间：2022-09-18

- Preparation and Characterization of Quantum Dots-tagged Self-assembly Nanoparticles
- Polymer Bulletin Vol. 20, Issue 6, Pages: 38-44(2007)
- 作者机构：
  
  天津大学材料科学与工程学院纳米生物技术研究所，天津　300072
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2007.06.006
  CLC：
- Published：2007-06，
扫描看全文
Yong YANG, Xiao-qing DONG, Lei ZHANG, Jin CHANG. Preparation and Characterization of Quantum Dots-tagged Self-assembly Nanoparticles. [J]. Polymer Bulletin 20(6):38-44(2007)
DOI：

Yong YANG, Xiao-qing DONG, Lei ZHANG, Jin CHANG. Preparation and Characterization of Quantum Dots-tagged Self-assembly Nanoparticles. [J]. Polymer Bulletin 20(6):38-44(2007) DOI： 10.14028/j.cnki.1003-3726.2007.06.006.

摘要

以EDC 为偶联剂

将胆酸接枝到赖氨酸改性的壳聚糖主链的氨基上

得到一系列胆酸取代度相同（4∙2%）而赖氨酸取代度不同（2∙3%

4∙4%

9∙6%）的双亲性壳聚糖衍生物（CA-LysCS）

利用FT-IR

H NMR 对其结构进行表征。CA-LysCS 在水相中自组装形成自聚集体。以芘为荧光探针对其自聚集行为进行了研究

结果显示制得的自聚集体具有较之小分子表面活性剂较低的CAC（1∙1×10

－2

～5∙3×10

－2

mg/mL）

表明自聚集体可在水相中形成稳定的胶束。且随着赖氨酸取代度的增加

CAC 值随之增大。以激光粒度仪对自聚集体水相中的粒径分布进行了研究

发现其平均粒径随着赖氨酸取代度的增大有所增加（164∙6～414∙3nm）。以三辛基氧化膦（TOPO）为包裹剂

制备了油溶性硫化镉（CdSe）绿色量子点。用制备的自聚集体对量子点进行了包裹

TEM 照片显示量子点位于自聚集体的疏水化核内。以荧光分光光度计对量子点的荧光特性进行了研究

发现包裹后量子点的荧光强度有所减弱。

Abstract

Various cholic acid modified lysine grafted chitosan(CA-LysCS) with the same degrees of substitute (DS) of cholic acid (4∙2%) and different degrees of substitute (DS) of Lysine(2∙3%

4∙7%

9∙3%) were synthesized with the EOC as the coupling reagent.Structural characteristics of these products were investigated using FT-IR and

HNMR.The critical aggregation concentration(CAC) of the self-aggregate of CA-LysCS were determined by measuring the fluorescence intensity of the pyrene as a fluorescent probe

which increased with increase of DS of Lysine in the range of 1∙1~5∙3×10

-2

mg/mL.The average particle size of self-aggregates in distilled water also increased with the increase of the DS of Lysine in the range of 164∙6~414∙3nm.These self-assembly nanoparticles were tagged using TOPO-capped green quantum dots (QDs).A transmission electron microscopy study showed that the quantum dots located in the hydrophobic core of the micelles.The flurescence intensity of green Quantum dots decreased after encapsulated mainly due to the covering of the micelles.

关键词

壳聚糖胆酸赖氨酸纳米粒子自聚集量子点（QDs）胶束

Keywords

ChitosanCholic acidL-LysineNanoparticlesSelf-assemblyQuantum dots

references

更多指标>

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Preparation of Maleoyl Chitosan Nanoparticles by Self-Assembly and their pH Responsability

Preparation of Poly(acrylic acid)/Graphene Oxide-Chitosan Composite Membrane and the Adsorption and Separation on Dyes

Preparation and Catalytic Properties of Carbon Dioxide-assisted Chitosan/Silver Hydrogel Beads

Research Progress on in vivo Degradation and Metabolism Assessment of Carboxymethyl Chitosan-based Biomaterials

Study on the Preparation and Properties of Water-soluble Chitosan Modified Cotton Fabric via Layer-by-layer Self-assembly Process

Related Author

No data

Related Institution

Key Laboratory of Rubber-plastics of Ministry of Education/Shandong Provincial Key Laboratory of Rubber-plastics , Qingdao University of Science & Technology

Fujian Key Laboratory of Novel Functional Textile Fibers and Materials, Minjiang University

Fujian Jinhuang Environmental Protection Technology Co.,Ltd.

School of Material Science and Chemical Engineering, Ningbo University

School of Materials and Chemical Engineering, Ningbo University of Technology

⁰