Advances in Asymmetric Michael Addition by Polymer-Supported Chiral Catalysts

Shi-ying ZHANG; Guan-zhong LU; Yun GUO

doi:10.14028/j.cnki.1003-3726.2007.12.002

您当前的位置：

首页 >

文章列表页 >

Advances in Asymmetric Michael Addition by Polymer-Supported Chiral Catalysts

更新时间：2022-09-18

- Advances in Asymmetric Michael Addition by Polymer-Supported Chiral Catalysts
- Polymer Bulletin Vol. 20, Issue 12, Pages: 49-55(2007)
- 作者机构：
  
  1.上海商学院实验中心，上海　201400
  2.华东理工大学工业催化研究所，上海　200237
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2007.12.002
  CLC：
- Published：2007-12，
扫描看全文
Shi-ying ZHANG, Guan-zhong LU, Yun GUO. Advances in Asymmetric Michael Addition by Polymer-Supported Chiral Catalysts. [J]. Polymer Bulletin 20(12):49-55(2007)
DOI：

Shi-ying ZHANG, Guan-zhong LU, Yun GUO. Advances in Asymmetric Michael Addition by Polymer-Supported Chiral Catalysts. [J]. Polymer Bulletin 20(12):49-55(2007) DOI： 10.14028/j.cnki.1003-3726.2007.12.002.

摘要

高分子手性催化剂用于不对称有机合成，它易与产物分离、可通过适当的处理后回收重复使用；具有毒性或气味的手性催化剂支载在高分子上后，使用更加安全和方便；而且，适当结构的高分子聚合物可以为不对称反应提供更有利的微环境，提高立体选择性。正是这些优点，高分子手性催化剂的研究越来越受到人们的关注。不对称Michael 反应是形成手性碳-碳、碳-杂键的重要反应，在有机合成和药物合成中起着重要的作用。本文综述了近年来的高分子手性催化剂在Michael 反应中的应用及最新进展。

Abstract

Polymer-supported chiral catalysts have broad applications in organic synthesis. The primary advantage is their ease of separation from the reaction mixture which allows very efficient recovery and reuse of the catalysts. When toxic or odorous reagents are attached to polymer supports

handling and processing of these chemicals becomes much safer and simpler. Moreover

the proper polymer may provide a respectively small space for asymmetric reaction

enhancing stereo-selectivity. So polymer-supported chiral catalysts have attracted more and more attention. Asymmetric Micheal reaction

an important carbon-carbon and carbon-hetero atom forming reaction

plays an essential role in organic synthesis and drug synthesis. In this paper

their application and the latest progress in Michael reaction were reviewed.

关键词

手性催化剂高分子支载Michael 反应

Keywords

Chiral catalystPolymer-supportedMichael reaction

references

更多指标>

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Advances in the Asymmetric Synthesis of α-Amino Acids Catalysed by Polymer-supported Chiral Cinchona Phase Transfer Catalysts

Advances in Asymmetric Catalysis Reaction by Polymer Supported Cinchona Alkaloid

Related Author

No data

Related Institution

State Key Laboratory of Functional Polymer Materials for Adsorption and Separation,Institute of Polymer Chemistry, Nankai University

Institute of polymer chemistry, North-West Normal University

⁰