In recent years

DNA nanotechnology has become a highly interdisciplinary research field

including such as life science

chemistry

physics

materials science and nanotechnology

and many other fields. Based on DNA self-assembly technology

people have constructed a series of molecular devices and materials. As a kind of smart and dynamic materials

supramolecular DNA hydrogels have potential applications in the biomedical field. This review highlights the recent important study about the self-assembled strategies

dynamic responsiveness and biomedical applications of supramolecular DNA hydrogels.