Research Progress in Hemocompatibility of Surface Modified Polypropylene

Bing CAI; Yue-xin HU; Xiang-yan HAN; Liang-cai LEI

doi:10.14028/j.cnki.1003-3726.2016.01.005

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Research Progress in Hemocompatibility of Surface Modified Polypropylene

更新时间：2022-09-12

- Research Progress in Hemocompatibility of Surface Modified Polypropylene
- Polymer Bulletin Vol. 29, Issue 1, Pages: 31-38(2016)
- 作者机构：
  
  辽宁石油化工大学化学化工与环境学部，抚顺 113001
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2016.01.005
  CLC：
- Published：20 January 2016，
  
  Received：16 March 2015，
  
  Revised：14 June 2015，
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Bing CAI, Yue-xin HU, Xiang-yan HAN, Liang-cai LEI. Research Progress in Hemocompatibility of Surface Modified Polypropylene. [J]. Polymer Bulletin 29(1):31-38(2016)
DOI：

Bing CAI, Yue-xin HU, Xiang-yan HAN, Liang-cai LEI. Research Progress in Hemocompatibility of Surface Modified Polypropylene. [J]. Polymer Bulletin 29(1):31-38(2016) DOI： 10.14028/j.cnki.1003-3726.2016.01.005.

摘要

聚丙烯具有价格低廉、无毒、易于加工等优点

使其在许多领域得到广泛的应用。但是聚丙烯自身有较强的疏水性

与血液相接触时

血浆蛋白会在材料表面大量吸附

诱发血小板的粘附和聚集

从而造成凝血和溶血的发生。在生物医用材料的应用过程中

血液相容性是限制材料能否长期应用的关键因素。本文综述了表面改性法提高聚丙烯血液相容性的研究现状、表面改性方法和常用的大分子单体

并分析了当前聚丙烯表面改性研究存在的问题

展望了具有良好血液相容性聚丙烯的发展前景。

Abstract

Polypropylene (PP) is one of the widely used materials in medical apparatus and instruments

owing to its inexpensive

non-toxic and excellent mechanical properties. When hydrophobic polypropylene is exposed to blood

plasma proteins are adsorbed to the surface

and then surface-induced platelet adhesion

subsequent thrombus and hemolysis occur. Hemocompatibility is one of major problems that limit the long period application of biomedical materials. In this paper

the recent progress of the surface modification of polypropylene

the methods and monomers to improve hemocompatibility are reviewed. Meanwhile

limitation of the modification and the prospect of polypropylene with hemocompatibility were presented.

关键词

血液相容性聚丙烯表面改性生物医用高分子材料

Keywords

HemocompatibilityPolypropyleneSurface modificationBiomedical polymer materials

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