The Research Progress of Hydrogel toward Artificial Cornea

You-lan ZENG; Cun JIANG; Peng SUN; Wen-hao LU; Quan-yuan ZHANG; Zu-shun XU

doi:10.14028/j.cnki.1003-3726.2016.08.011

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The Research Progress of Hydrogel toward Artificial Cornea

更新时间：2022-09-12

- The Research Progress of Hydrogel toward Artificial Cornea
- Polymer Bulletin Vol. 29, Issue 8, Pages: 100-107(2016)
- 作者机构：
  
  湖北大学材料科学与工程学院功能材料绿色制备与应用教育部重点实验室，武汉 430062
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2016.08.011
  CLC：
- Published：20 August 2016，
  
  Received：24 November 2015，
  
  Revised：21 February 2016，
扫描看全文
You-lan ZENG, Cun JIANG, Peng SUN, Wen-hao LU, Quan-yuan ZHANG, Zu-shun XU. The Research Progress of Hydrogel toward Artificial Cornea. [J]. Polymer Bulletin 29(8):100-107(2016)
DOI：

You-lan ZENG, Cun JIANG, Peng SUN, Wen-hao LU, Quan-yuan ZHANG, Zu-shun XU. The Research Progress of Hydrogel toward Artificial Cornea. [J]. Polymer Bulletin 29(8):100-107(2016) DOI： 10.14028/j.cnki.1003-3726.2016.08.011.

摘要

理想的人工角膜植入材料要求物理化学性质稳定、生物相容性好、透光性高以及透气性好等，同时还应具有一定的折射能力，使得植入后能够达到矫正视力的目的。水凝胶因良好的生物相容性，及其对水溶性代谢产物如葡萄糖、营养物质、氧气等高的透过性，在眼科材料领域得到了非常广泛的应用。本文主要介绍了水凝胶材料在人工角膜上的研究进展，包括天然高分子水凝胶、合成高分子水凝胶、IPN互穿网络水凝胶以及高折射率有机-无机复合水凝胶。

Abstract

Ideal keratoprosthesis implantation material requires stable physical and chemical properties

excellent biological compatibility

high transparency

good air permeability and has certain refractive power

which make the implanted to reach the corrected visual acuity. Hydrogel has been widely used in the department of Ophthalmology

due to good biocompatibility and high permeability to water soluble metabolites such as glucose

nutrients

oxygen and so on. In this article

We provide a critical review of research and development of hydrogel-based artificial cornea from a materials perspective

including natural polymer hydrogels

synthetic polymer hydrogels

interpenetrating polymer network hydrogels and organic-inorganic composite hydrogels with high refractive index.

关键词

人工眼角膜水凝胶高折光率IPN

Keywords

Artificial corneaHydrogelHigh refractive indexIPN

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