Biomedical Applications of Porous Organic Polymers

Wu-ji CHEN; Jia GUO

doi:10.14028/j.cnki.1003-3726.2018.06.012

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Biomedical Applications of Porous Organic Polymers

更新时间：2022-09-05

- Biomedical Applications of Porous Organic Polymers
- Polymer Bulletin Vol. 31, Issue 6, Pages: 129-142(2018)
- 作者机构：
  
  聚合物分子工程国家重点实验室复旦大学高分子科学系, 上海 200438
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2018.06.012
  CLC：
- Published：20 June 2018，
  
  Received：06 February 2018，
  
  Revised：30 March 2018，
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Wu-ji CHEN, Jia GUO. Biomedical Applications of Porous Organic Polymers. [J]. Polymer Bulletin 31(6):129-142(2018)
DOI：

Wu-ji CHEN, Jia GUO. Biomedical Applications of Porous Organic Polymers. [J]. Polymer Bulletin 31(6):129-142(2018) DOI： 10.14028/j.cnki.1003-3726.2018.06.012.

摘要

多孔有机聚合物（Porous Organic Polymers，POPs）是近些年来发展迅速的新兴材料，是高分子学科领域中最受关注的研究热点之一。基于其化学合成的多样性和可设计性，不同的功能单元可以通过预先的结构设计或是功能化后修饰等策略，使其具备在多个领域应用的功能和性质。由于其展现的较大应用潜力和发展前景，POPs材料也开始吸引了越来越多的研究兴趣将其应用于生物医用领域。本文重点展示了POPs基材料在药物输送、光疗、酶固定、病理诊断和免疫分析、生物传感和成像等生物医用方面的最新成果，同时也对其今后的挑战和发展进行了讨论和评述。

Abstract

Porous Organic Polymers (POPs) are emerging porous materials that have been developed rapidly over recent years

and have been one of the most concerned subjects in the field of polymer science. Given the versatile and tailor-made chemistry

a variety of functional units can be introduced into porous organic polymer materials through the structural predesign or post-modification to render POPs the specific functions for multiple applications. As they have shown the great potential and prospective future

POPs have also evoked increasing interest and desire of exploration in the biomedical field. This article gives a survey of the latest progress in use of POPs for drug delivery

phototherapy

enzyme immobilization

pathology diagnostics and immunoassays

biosensing

and bioimaging. Afterwards

the current challenges and development of researches are discussed as a conclusion to the mini review.

关键词

多孔材料生物医用共价有机骨架共轭微孔聚合物

Keywords

Porous materialsBiomedical applicationsCovalent organic frameworksConjugated microporous polymers

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