In recent years

polymer conjugated drugs have attracted much attention due to their good stability

excellent sustained release and specific drug targeting. Generally

they can be prepared by two methods: first monomer polymerization then drug conjugating

and first making drug conjugated into monomers then polymerization. Based on this classification

the recent research progress of polymer conjugated drugs is reviewed. The biodegradable polymers as the carrier of polymer conjugated drugs have good biodegradability in vivo and can avoid a second major surgical procedure. The post-polymerization method of drug conjugated monomers is convenient for its simple procedure with high drug-loading. These advantages make them be two important developing directions in the research area of polymer conjugated drugs. Especially

assembling carrier preparation and drug loading into one-step process to prepare biodegradable polymer conjugated drugs is very noteworthy.