Recent Advance in Conjugated Polymer Contrast Agents for Photoacoustic Imaging

Yun-bin XIAO; Hong-yi SHI; Fu-bin WEN; Bin WANG

doi:10.14028/j.cnki.1003-3726.2018.08.009

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Recent Advance in Conjugated Polymer Contrast Agents for Photoacoustic Imaging

更新时间：2022-09-05

- Recent Advance in Conjugated Polymer Contrast Agents for Photoacoustic Imaging
- Polymer Bulletin Vol. 31, Issue 8, Pages: 48-52(2018)
- 作者机构：
  
  1.中国科学院广州化学研究所，广州　510650
  2.中国科学院纤维素化学重点实验室，广州　510650
  3.中国科学院大学，北京　100049
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2018.08.009
  CLC：
- Published：20 August 2018，
  
  Received：03 November 2017，
  
  Revised：15 June 2018，
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Yun-bin XIAO, Hong-yi SHI, Fu-bin WEN, Bin WANG. Recent Advance in Conjugated Polymer Contrast Agents for Photoacoustic Imaging. [J]. Polymer Bulletin 31(8):48-52(2018)
DOI：

Yun-bin XIAO, Hong-yi SHI, Fu-bin WEN, Bin WANG. Recent Advance in Conjugated Polymer Contrast Agents for Photoacoustic Imaging. [J]. Polymer Bulletin 31(8):48-52(2018) DOI： 10.14028/j.cnki.1003-3726.2018.08.009.

摘要

光声成像是一种新兴医学影像成像技术。作为一种非侵入式和非电离式的成像技术，光声成像具有高分辨率、高对比度和穿透深度高的特点。这种成像技术在对组织进行诊断时需要加入造影剂与组织相结合才能产生显著的光声信号。然而，目前光声成像技术仍缺乏合适的造影剂，制约了其在生物医学领域的应用。共轭聚合物因其具有优异的光热性能和良好的生物相容性，被广泛应用于光声成像领域。本文综述了共轭聚合物作为外源性造影剂在光声成像领域的应用的研究进展，并对共轭聚合物光声造影剂的发展进行了展望。

Abstract

Photoacoustic imaging (PAI) is a novel medical imaging technology. As a non-invasive and non-ionizing imaging technology

PAI features high resolution

high contrast and high penetration depth. In order to produce a significant photoacoustic signal in the diagnosis of tissue

this imaging technique requires to append contrast agent for interacting with tissues. However

the lack of appropriate contrast agents limits the current application of PAI in the biomedical field. Conjugated polymers are widely utilized for PAI due to their hallmarks of excellent optical performance and good compatibility. Herein

we review the application of conjugated polymers as exogenous contrast agents in PAI and the development of conjugated polymers for contrast agents is prospected.

关键词

光声成像共轭聚合物造影剂

Keywords

Photoacoustic imagingConjugated polymersContrast agents

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Institute of Chemistry, Chinese Academy of Sciences

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