Progress in Self-Assembly and Functionalization of Protein-based Macrocycles

Qiang-qiang XU; Han-lin GONG; Jie SHANG; Tie-zheng PAN; Yan GE; Zhen-hui QI

doi:10.14028/j.cnki.1003-3726.2019.10.013

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Progress in Self-Assembly and Functionalization of Protein-based Macrocycles

更新时间：2022-09-05

- Progress in Self-Assembly and Functionalization of Protein-based Macrocycles
- Polymer Bulletin Vol. 32, Issue 10, Pages: 119-129(2019)
- 作者机构：
  
  陕西省柔性电子与健康科学国际联合研究中心，中德空间生物材料与技术转化联合实验室，西北工业大学生命学院，西安 710072
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2019.10.013
  CLC：
- Published：20 October 2019，
  
  Received：28 May 2019，
  
  Revised：05 July 2019，
扫描看全文
Qiang-qiang XU, Han-lin GONG, Jie SHANG, Tie-zheng PAN, Yan GE, Zhen-hui QI. Progress in Self-Assembly and Functionalization of Protein-based Macrocycles. [J]. Polymer Bulletin 32(10):119-129(2019)
DOI：

Qiang-qiang XU, Han-lin GONG, Jie SHANG, Tie-zheng PAN, Yan GE, Zhen-hui QI. Progress in Self-Assembly and Functionalization of Protein-based Macrocycles. [J]. Polymer Bulletin 32(10):119-129(2019) DOI： 10.14028/j.cnki.1003-3726.2019.10.013.

摘要

主要介绍了生物蛋白大环自组装及其功能化研究的新进展，针对目前开发较为深入的蛋白大环结构特点、制备方法及其功能化探索等方面进行分析和评述。蛋白大环作为一类生物源高分子环状结构，其研究是高分子化学、大环化学的延伸与拓展。蛋白质大环结构为功能性高分子的构筑提供了全新的材料设计与研究思路。随着蛋白自组装行为的动力学和热力学机制得到更为深入的解析，操控蛋白自组装过程将变得更为娴熟。

Abstract

This review focuses on the recent progress of self-assembly and functionalization of protein-based macrocycles. Taking the most popular protein macrocycles as example

the structural features

fabrication strategies and functions of these well-explored protein-macrocycles were analyzed and compared. As a new kind of biogenic polymeric macrocycle

protein-macrocycles serve as the evolutionary product of biopolymer science and macrocyclic chemistry. The protein-macrocyclic structure provides a novel design material and construction platform for fabrication of functional polymers. With the accumulated knowledge of kinetics and thermodynamic behaviors

the manipulation of the self-assembly process of protein-macrocycles will become skilled.

关键词

蛋白大环生物高分子大环化学自组装

Keywords

Protein-MacrocycleBiopolymerMacrocycleSelf-Assembly

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