Recent Advances in Polyisobutylene-based Bioinert Elastomers

Yan-hao ZHAO; Yu-wei SHANG; Yi-bo WU; Hao WANG; Shu-xin LI; Dan YANG

doi:10.14028/j.cnki.1003-3726.2020.01.003

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Recent Advances in Polyisobutylene-based Bioinert Elastomers

更新时间：2022-08-31

- Recent Advances in Polyisobutylene-based Bioinert Elastomers
- Polymer Bulletin Vol. 33, Issue 1, Pages: 24-30(2020)
- 作者机构：
  
  1.北京石油化工学院材料科学与工程学院特种弹性体复合材料北京市重点实验室,北京 102617
  2.北京化工大学材料科学与工程学院,北京 100029
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2020.01.003
  CLC：
- Published：20 January 2020，
  
  Received：26 March 2019，
  
  Revised：21 October 2019，
扫描看全文
Yan-hao ZHAO, Yu-wei SHANG, Yi-bo WU, Hao WANG, Shu-xin LI, Dan YANG. Recent Advances in Polyisobutylene-based Bioinert Elastomers. [J]. Polymer Bulletin 33(1):24-30(2020)
DOI：

Yan-hao ZHAO, Yu-wei SHANG, Yi-bo WU, Hao WANG, Shu-xin LI, Dan YANG. Recent Advances in Polyisobutylene-based Bioinert Elastomers. [J]. Polymer Bulletin 33(1):24-30(2020) DOI： 10.14028/j.cnki.1003-3726.2020.01.003.

摘要

聚异丁烯由于其全饱和结构

有且仅存在碳氢键

所以聚异丁烯基材料大多具有良好的生物稳定性和相容性。近年来关于聚异丁烯基生物惰性弹性体的研究取得了许多的进展

包括PIB-poly(methyl methacrylate) (PMMA)用于骨关节粘合剂、PIB-cyanoacrylate (CA)用于腰椎间盘替换、基于PIB的两亲网络(APNs)用于免疫隔离膜、聚异丁烯基聚氨酯(PU)及聚脲的发展。另外

在poly(styrene-

-isobutylene-

-styrene)(SIBS)生物医用材料方面也取得了重要进展

其中包括SIBS应用于药物释放载体、青光眼导流管、心脏瓣膜以及人工血管等方面。最后

本文也对聚异丁烯基生物惰性弹性体的未来发展进行了展望。

Abstract

Polyisobutylene has a good biocompatibility due to its fully saturated structure and the presence of only carbon-hydrogen bonds. Polyisobutylene-based bioinert elastomers have made many advances in recent years

including PIB-poly(methyl methacrylate) (PMMA) for toughening of bone cements; PIB-cyanoacrylate (CA) for intervertebral disk replacement; PIB-based amphipathic networks(APNs) for immunoisolatory membranes and the development of polyisobutylene based polyurethanes(PU) and polyureas. Significant advances have also been made in poly(styrene-

-isobutylene-

-styrene) biomedical materials

including SIBS for drug delivery vehicles

glaucoma diversion tubes

heart valves

and artificial blood vessels. It also looks forward to the future development of polyisobutylene-based bioinert elastomers.

关键词

聚异丁烯SIBS生物医用材料生物惰性弹性体

Keywords

PolyisobutyleneSIBSBiomedical materialsBioinert elastomer

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Related Institution

School of Materials Science and Engineering , Zhengzhou University

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