Review of Performance Defects and Their Related Research Progress on Plain PMMA Bone Cement

Ding-ze CHUAN; Ling ZHANG; Jin-kun LIU

doi:10.14028/j.cnki.1003-3726.2021.01.002

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Review of Performance Defects and Their Related Research Progress on Plain PMMA Bone Cement

更新时间：2022-08-30

- Review of Performance Defects and Their Related Research Progress on Plain PMMA Bone Cement
- Polymer Bulletin Vol. 34, Issue 1, Pages: 10-16(2021)
- 作者机构：
  
  1.昆明理工大学材料科学与工程学院,昆明 650093
  2.云南中烟工业有限责任公司,昆明 650231
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2021.01.002
  CLC：
- Published：20 January 2021，
  
  Received：26 June 2019，
  
  Revised：21 September 2020，
扫描看全文
Ding-ze CHUAN, Ling ZHANG, Jin-kun LIU. Review of Performance Defects and Their Related Research Progress on Plain PMMA Bone Cement. [J]. Polymer Bulletin 34(1):10-16(2021)
DOI：

Ding-ze CHUAN, Ling ZHANG, Jin-kun LIU. Review of Performance Defects and Their Related Research Progress on Plain PMMA Bone Cement. [J]. Polymer Bulletin 34(1):10-16(2021) DOI： 10.14028/j.cnki.1003-3726.2021.01.002.

摘要

聚甲基丙烯酸甲酯(PMMA)骨水泥是一种用于治疗脊柱压缩性骨折和固定关节假体的植入材料。临床上运用时仍有三大主要缺陷:甲基丙烯酸甲酯(MMA)聚合放热时会引起的骨组织热坏死、微裂纹产生及失稳扩展会导致力学性能较差

以及与骨组织机械连锁在长期移植后的失效问题。本文依照PMMA骨水泥的上述性能缺陷

提出了有针对性的研究思路

总结了经典研究案例、讨论了具体成果并凝练了今后的研究趋势。同时基于性能缺陷的本质

提出了理想的改性研究需要达到的目的

为今后新型PMMA 骨水泥能用于临床奠定理论和实验基础。

Abstract

PMMA bone cement is an implant material used for the treatment of spinal fractures and the fixation of joint prostheses. Three main defects exposed in clinical application can be concluded as: the exothermic polymerization of MMA leads to the thermal necrosis of bone tissues

the micro-crack growth from internal defects brings about the poor mechanical performance

the physical bonding to bone in terms of the mechanical interlocking lowered the long-term stability of implants. According to these mentioned performance defects

this paper proposes targeted scientific research thoughts

sums up the typical examples of current research

discusses detailed research findings and concluded current research directions. Besides that

based on the nature of performance defects

this paper also proposes the significance of ideal modification and its purpose

lays the theoretical and experimental foundation for future clinical application of new type PMMA bone cement.

关键词

聚甲基丙烯酸甲酯骨水泥性能缺陷固化放热力学性能生物活性

Keywords

PMMA bone cementPerformance defectsCuring exothermMechanical propertiesBioactivity

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