Application of Laser Scanning Confocal Microscopy in the Study of Polymer Science

Ying-ying ZHANG; Yi GUO; Lie SHEN

doi:10.14028/j.cnki.1003-3726.2022.01.010

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Application of Laser Scanning Confocal Microscopy in the Study of Polymer Science

更新时间：2022-09-09

- Application of Laser Scanning Confocal Microscopy in the Study of Polymer Science
- Polymer Bulletin Vol. 35, Issue 1, Pages: 78-85(2022)
- 作者机构：
  
  高分子合成与功能构造教育部重点实验室,浙江大学高分子科学与工程学系,杭州 310027
- 作者简介：
- 基金信息：
- DOI：10.14028/j.cnki.1003-3726.2022.01.010
  CLC：
- Published：20 January 2022，
  
  Received：14 October 2020，
  
  Revised：08 May 2021，
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Ying-ying ZHANG, Yi GUO, Lie SHEN. Application of Laser Scanning Confocal Microscopy in the Study of Polymer Science. [J]. Polymer Bulletin 35(1):78-85(2022)
DOI：

Ying-ying ZHANG, Yi GUO, Lie SHEN. Application of Laser Scanning Confocal Microscopy in the Study of Polymer Science. [J]. Polymer Bulletin 35(1):78-85(2022) DOI： 10.14028/j.cnki.1003-3726.2022.01.010.

摘要

激光扫描共聚焦显微技术作为一种深层形态结构分析的重要研究方法

避免了繁琐的实验操作以及对样品的破坏

可直接给出材料内部结构的三维图像

在生物学、医学、材料科学和冶金学等研究领域都有广泛的应用。本文阐述了激光扫描共聚焦显微镜的工作原理及技术优势

综述了激光扫描共聚焦显微技术在高分子科学研究领域的应用进展

包括聚合物多组分体系、聚合物颗粒、聚合物膜、嵌段共聚物自组装以及药物控释表征

以期为更多科研人员提供有益参考。

Abstract

Laser scanning confocal microscopy is an important research method for the analysis of internal structure of materials without complex experimental operation and prior sample destruction. It can give a three-dimensional image of the internal structure directly and is widely used in the research of biology

medicine

materials science and metallurgy

etc. This paper introduced the working principle and advantages of laser scanning confocal microscope. Moreover

the application progress in the field of polymer science was summarized

which includes polymer multi-component systems

polymer particles

polymer films

self-assembly of block copolymers

and controlled release of drugs

in order to provide useful reference for more scientific researchers.

关键词

激光扫描共聚焦显微镜高分子科学应用

Keywords

Laser scanning confocal microscopyPolymer ScienceApplication

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