Unnatural biomacromolecule metamaterials are materials with unique chemical structure and functional properties

whose functions can surpass biomacromolecules in nature. It is a new research frontier in the field of polymer science. Such materials can be artificially engineered and modified through (dynamic) chemical modification

genetic engineering

and supramolecular self-assembly

resulting in exceptional optical

electronic

and mechanical properties

as well as excellent flexibility

responsiveness

controllability

and diversity. Therefore

unnatural biomacromolecular metamaterials have broad application prospects in the fields of biology

medicine and materials. Based on the above

this review narrates the design and synthesis methods of unnatural biomacromolecule metamaterials

and summarizes their applications in biosensing

catalysis

medicine

nanomaterials and other fields

emphasizing their importance in solving complex problems in different fields.