卤胺高分子抗菌材料的研究进展与应用前景

赵鑫玉; 丁放; 任学宏

doi:10.14028/j.cnki.1003-3726.2026.25.312

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卤胺高分子抗菌材料的研究进展与应用前景

综述 | 更新时间：2026-03-21

- 卤胺高分子抗菌材料的研究进展与应用前景
- Research Progress and Application Prospects of N-halamine Antibacterial Polymeric Materials
- 高分子通报 2026年39卷第4期页码：585-599
- 作者机构：
  
  武汉纺织大学纺织科学与工程学院　武汉 430200
  南通大学纺织服装学院　南通 226019
- 作者简介：
  
  xuehongr@hotmail.com
- 基金信息：
  
  湖北省中央引导地方科技发展专项(2022BGE253)
- DOI：10.14028/j.cnki.1003-3726.2026.25.312
  中图分类号：
- 收稿：2025-10-30，
  
  录用：2026-01-05，
  
  网络首发：2026-03-06，
  
  纸质出版：2026-04-20
- 稿件说明：
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赵鑫玉, 丁放, 任学宏. 卤胺高分子抗菌材料的研究进展与应用前景. 高分子通报, 2026, 39(4), 585–599.

Zhao, X. Y.; Ding, F.; Ren, X. H. Research progress and application prospects of N-halamine antibacterial polymeric materials. Polym. Bull. (in Chinese), 2026, 39(4), 585–599.
赵鑫玉, 丁放, 任学宏. 卤胺高分子抗菌材料的研究进展与应用前景. 高分子通报, 2026, 39(4), 585–599. DOI： 10.14028/j.cnki.1003-3726.2026.25.312.

Zhao, X. Y.; Ding, F.; Ren, X. H. Research progress and application prospects of N-halamine antibacterial polymeric materials. Polym. Bull. (in Chinese), 2026, 39(4), 585–599. DOI： 10.14028/j.cnki.1003-3726.2026.25.312.

摘要

卤胺高分子是一类具有广谱抗菌性能的高分子材料，因其独特的卤胺结构而展现出高效、长效的抗菌活性。近年来，随着材料科学和抗菌技术的快速发展，卤胺高分子在医疗、水处理、纺织品和食品包装等领域的应用研究取得了显著进展。本文综述了卤胺单体和卤胺高分子的种类、制备方法及其在医用防护材料、纺织品、医疗器械涂层、水/空气过滤材料等领域的研究进展，重点探讨了卤胺高分子在抗菌敷料、涂料、口罩、口腔种植体等医用防护产品中的应用，以及其在抗生物膜形成和抗感染方面的优势。此外，还分析了卤胺高分子实际应用中面临的挑战，如长效稳定性和生物相容性等，并展望了未来发展方向，包括开发新型卤胺衍生物、结合纳米技术制备复合抗菌材料以及推动临床应用。卤胺高分子作为一种高效抗菌材料，在医疗防护和公共卫生领域具有广阔的应用前景。

Abstract

-halamine polymers are a class of polymeric materials with broad-spectrum antibacterial properties

which exhibit highly efficient and long-

lasting antibacterial activity due to their unique

-halamine structure. In recent years

with the rapid development of materials science and antibacterial technology

significant progress has been made in the application of

-halamine polymers in fields such as medical care

water treatment

textiles

food packaging and so on. This work reviews the types

preparation methods of

-halamine monomers and polymers

as well as their research progress in medical protective materials

textiles

medical device coatings

water/air filtration materials

etc

. It focuses on discussing the application of

-halamine polymers in medical protective products such as antibacterial dressings

coatings

masks

and oral implants

as well as their advantages in anti-biofilm formation and anti-infection. In addition

the challenges

-halamine polymers faced in practical applications

such as long-term stability and biocompatibility are analyzed. The future development directions

including the new

-halamine derivatives

the preparation of composite antibacterial materials by combining nanotechnology

and the promotion of clinical applications have also been prospected. As efficient antibacterial materials

-halamine polymers have broad application prospects in medical protection and public health fields.

关键词

Keywords

references

Hao, Y. J. ; Liu, S. ; Cai, H. T. ; Zhang, Q. Y. ; Gao, G. ; Hao, X. F . A silicone with one quaternary ammonium salt and three N -halamine sites in the repeating unit for improved antibiotic ability on submicrospheres . Colloid Interface Sci. Commun. , 2023 , 56 , 100731 .

Luo, H. ; Yin, X. Q. ; Tan, P. F. ; Gu, Z. P. ; Liu, Z. M. ; Tan, L . Polymeric antibacterial materials: design, platforms and applications . J. Mater. Chem. B , 2021 , 9 ( 12 ), 2802 – 2815 .

Olmos, D. ; González-Benito, J . Polymeric materials with antibacterial activity: a review . Polymers , 2021 , 13 ( 4 ), 613 .

Liu, J. L. ; Zhao, J. ; Qu, L. Y. ; Jiang, Z. M. ; Xu, Y. J . Scalable one-pot synthesis of hindered amine-functionalized melamine resin microspheres as robust N -halamine antimicrobial platforms . Chem. Eng. J. , 2025 , 522 , 168179 .

Fu, J. N. ; Wang, C. F. ; Liu, X. M. ; Zhu, S. L. ; Zheng, Y. F. ; Li, Z. Y. ; Cui, Z. D. ; Zhang, Y. ; Jiang, H. ; Cao, Y. P. ; Chu, P. K. ; Wu, S. L . Smart responsive materials for antibacterial therapy: progress, opportunities, and challenges . Prog. Mater. Sci. , 2026 , 155 , 101532 .

Wu, Y. Z. ; Liu, P. ; Mehrjou, B. ; Chu, P. K . Interdisciplinary-inspired smart antibacterial materials and their biomedical applications . Adv. Mater. , 2024 , 36 ( 17 ), 2305940 .

Wang, C. Q. ; Xu, P. ; Li, X. X. ; Zheng, Y. H. ; Song, Z. M . Research progress of stimulus-responsive antibacterial materials for bone infection . Front. Bioeng. Biotechnol. , 2022 , 10 , 1069932 .

Lan, G. B. ; Chu, X. ; Li, C. H. ; Zhang, C. ; Miao, G. Q. ; Li, W. Y. ; Peng, F. ; Zhao, X. D. ; Li, M . Surface modification of titanium with antibacterial porous N -halamine coating to prevent peri-implant infection . Biomed. Mater. , 2023 , 18 ( 1 ), 015005 .

李平 , 董阿力德尔图 , 孙梓嘉 , 高歌 . N- 卤胺类高分子与纳米抗菌材料的制备及应用 . 化学进展 , 2017 , 29 ( S2 ), 318 – 328 .

Dong, A. ; Wang, Y. J. ; Gao, Y. Y. ; Gao, T. Y. ; Gao, G . Chemical insights into antibacterial N- halamines . Chem. Rev. , 2017 , 117 ( 6 ), 4806 – 4862 .

Smola-Dmochowska, A. ; Lewicka, K. ; Macyk, A. ; Rychter, P. ; Pamuła, E. ; Dobrzyński, P . Biodegradable polymers and polymer composites with antibacterial properties . Int. J. Mol. Sci. , 2023 , 24 ( 8 ), 7473 .

Guo, M. M. ; Zhang, X. H. ; Ismail, B. B. ; He, Q. ; Yang, Z. H. ; Xianyu, Y. ; Liu, W. T. ; Zhou, J. W. ; Ye, X. Q. ; Liu, D. H . Super antibacterial capacity and cell envelope-disruptive mechanism of ultrasonically grafted N -halamine PBAT/PBF films against escherichia coli . ACS Appl. Mater. Interfaces , 2023 , 15 ( 32 ), 38910 – 38929 .

Parcheta, M. ; Sobiesiak, M . Preparation and functionalization of polymers with antibacterial properties-review of the recent developments . Materials , 2023 , 16 ( 12 ), 4411 .

Yoshinaga, Y. ; Yoshida, Y . Stereospecific radical polymerization of methacrylate bearing oxazolidone structure and improvement of glass transition temperature of urethane methacrylate copolymers . J. Polym. Sci. , 2023 , 61 ( 17 ), 2050 – 2059 .

Eknoian, M. W. ; Worley, S. D. ; Harris, J. M . New biocidal N -halamine-PEG polymers . J. Bioact. Compatible Polym. , 1998 , 13 ( 2 ), 136 – 145 .

Jia, Z. Q. ; Peng, W. J. ; Zhang, T. Q. ; Hao, S. ; Xu, X. ; Chen, Y. L. ; Li, S. D. ; Wen, J. P . Syntheses and applications of N- halamines antimicrobial agents . Mini Rev. Org. Chem. , 2022 , 19 ( 8 ), 955 – 967 .

Eknoian, M. W. ; Worley, S. D . New N- halamine biocidal polymers . J. Bioact. Compatible Polym. , 1998 , 13 ( 4 ), 303 – 314 .

Cai, Q. ; Bao, S. ; Zhao, Y. ; Zhao, T. Y. ; Xiao, L. H. ; Gao, G. ; Chokto, H. ; Dong, A . Tailored synthesis of amine N -halamine copolymerized polystyrene with capability of killing bacteria . J. Colloid Interface Sci. , 2015 , 444 , 1 – 9 .

Sun, Y. Y. ; Sun, G . Durable and refreshable polymeric N -halamine biocides containing 3-(4′-vinylbenzyl)-5, 5-dimethylhydantoin . J. Polym. Sci. Part A Polym. Chem. , 2001 , 39 ( 19 ), 3348 – 3355 .

Sun, Y. Y. ; Sun, G . Synthesis, characterization, and antibacterial activities of novel N -halamine polymer beads prepared by suspension copolymerization . Macromolecules , 2002 , 35 ( 23 ), 8909 – 8912 .

Li, J. ; Huang, P. ; Cheng, X. Q. ; Wang, R. M. ; He, Y. F. ; Song, P. F . Amphiphilic N -halamine copolymer antibacterial nanoparticles with hydroge N -donor and hydroge N -acceptor . Appl. Surf. Sci. , 2024 , 666 , 160382 .

Eknoian, M. W. ; Worley, S. D. ; Bickert, J. ; Williams, J. F . Novel antimicrobial N -halamine polymer coatings generated by emulsion polymerization . Polymer , 1999 , 40 ( 6 ), 1367 – 1371 .

Cao, Z. B. ; Sun, Y. Y . Polymeric N -halamine latex emulsions for use in antimicrobial paints . ACS Appl. Mater. Interfaces , 2009 , 1 ( 2 ), 494 – 504 .

Li, X. L. ; Liu, Y. ; Jiang, Z. M. ; Li, R. ; Ren, X. H. ; Huang, T. S . Synthesis of an N -halamine monomer and its application in antimicrobial cellulose via an electron beam irradiation process . Cellulose , 2015 , 22 ( 6 ), 3609 – 3617 .

Kocer, H. B. ; Worley, S. D. ; Broughton, R. M. ; Huang, T. S . A novel N -halamine acrylamide monomer and its copolymers for antimicrobial coati ngs . React. Funct. Polym. , 2011 , 71 ( 5 ), 561 – 568 .

Kocer, H. B . Residual disinfection with N -halamine based antimicrobial paints . Prog. Org. Coat. , 2012 , 74 ( 1 ), 100 – 105 .

Chen, Z. B. ; Sun, Y. Y . N -halamine-based antimicrobial additives for polymers: preparation, characterization, and antimicrobial activity . Ind. Eng. Chem. Res. , 2006 , 45 ( 8 ), 2634 – 2640 .

Kocer, H. B. ; Akdag, A. ; Ren, X. H. ; Broughton, R. M. ; Worley, S. D. ; Huang, T. S . Effect of alkyl derivatization on several properties of N -halamine antimicrobial siloxane coatings . Ind. Eng. Chem. Res. , 2008 , 47 ( 20 ), 7558 – 7563 .

Ren, X. H. ; Kou, L. ; Liang, J. ; Worley, S. D. ; Tzou, Y. M. ; Huang, T. S . Antimicrobial efficacy and light stability of N -halamine siloxanes bound to cotton . Cellulose , 2008 , 15 ( 4 ), 593 – 598 .

Ren, X. ; Akdag, A. ; Zhu, C. ; Kou, L. ; Worley, S. ; Huang, T . Electrospun polyacrylonitrile nanofibrous biomaterials . J. Biomed. Mater. Res. Part A , 2009 , 91 ( 2 ): 385 –390 .

Li, J. ; Liu, Y. ; Jiang, Z. M. ; Ma, K. K. ; Ren, X. H. ; Huang, T. S . Antimicrobial cellulose modified with nanotitania and Cyclic N -halamine . Ind. Eng. Chem. Res. , 2014 , 53 ( 33 ), 13058 – 13064 .

Liang, J. ; Chen, Y. ; Barnes, K. ; Wu, R. ; Worley, S. D. ; Huang, T. S . N -halamine/quat siloxane copolymers for use in biocidal coatings . Biomaterials , 2006 , 27 ( 11 ), 2495 – 2501 .

Li, C. H. ; Gerile, S. ; Du, N. ; Zou, L. ; Wang, Z. Q. ; Liu, Y. F. ; Hou, J. L. ; Song, K. T. ; Xiao, Y. H. ; Ren, H. ; Kang, J. ; Dong, A. ; Xu, R . Multi-active-site antibacterial modification of dopamine-hyaluronic acid hydrogel with N -halamine for skin tissue engineering . Carbohydr. Polym. , 2025 , 358 , 123565 .

Khalid, R. ; Rosli, M. I. ; Zulkarnain, N. A. ; Sheikh Abdullah, S. R. ; Idris, M. I. ; Buhari, J . Assessing risks of chlorine usage as a disinfectant in drinking water treatment plant . Model. Earth Syst. Environ. , 2025 , 11 ( 4 ), 276 .

Joakim Larsson, D. G. ; Flach, C. F . Antibiotic resistance in the environment . Nat. Rev. Microbiol. , 2022 , 20 ( 5 ), 257 – 269 .

Coulliette, A. D. ; Enger, K. S. ; Weir, M. H. ; Rose, J. B . Risk reduction assessment of waterborne Salmonella and Vibrio by a chlorine contact disinfectant point-of-use device . Int. J. Hyg. Environ. Health , 2013 , 216 ( 3 ), 355 – 361 .

Ahmed, A. E. I. ; Cavalli, G. ; Bushell, M. E. ; Wardell, J. N. ; Pedley, S. ; Charles, K. ; Hay, J. N . New approach to produce water free of bacteria, viruses, and halogens in a recyclable system . Appl. Environ. Microbiol. , 2011 , 77 ( 3 ), 847 – 853 .

Liu, S. ; Yao, L. L. ; Wang, X. R. ; Zhao, G. Y. ; Li, F. ; Yao, B. J. ; Dong, Y. B . BODIPY and N- halamine-decorated covalent organic framework with synergistic antibacterial capabilities for sunlight-powered water sterilization . J. Mater. Chem. A , 2025 , 13 ( 6 ), 4530 – 4537 .

Kim, S. S. ; Jung, D. ; Choi, U. H. ; Lee, J . Antimicrobial m-aramid nanofibrous membrane for nonpressure driven filtration . Ind. Eng. Chem. Res. , 2011 , 50 ( 14 ), 8693 – 8697 .

Fu, S. J. ; Wang, Y. H. ; Tang, P. X . Fiber-supported biocidal porous organic polymer with high-density N -halamine structures for chlorine rechargeable water disinfection . ACS Appl. Polym. Mater. , 2023 , 5 ( 7 ), 5620 – 5629 .

Zhang, Y. ; Yin, M. L. ; Li, L. ; Fan, B. J. ; Liu, Y. ; Li, R. ; Ren, X. H. ; Huang, T. S. ; Kim, I. S . Construction of aerogels based on nanocrystalline cellulose and chitosan for high efficient oil/water separation and water disinfection . Carbohydr. Polym. , 2020 , 243 , 116461 .

Kong, Q. ; Ren, X. H. ; Li, Z. G . Three-dimensional porous structure on cotton fabric through the breath figure method with functions of self-cleaning and oil/water separation . Cellulose , 2023 , 30 ( 6 ), 3915 – 3930 .

Chan, J. F. ; Yuan, S. F. ; Chu, H. ; Sridhar, S. ; Yuen, K. Y . COVID-19 drug discovery and treatment options . Nat. Rev. Microbiol. , 2024 , 22 ( 7 ), 391 – 407 .

Parhiz, H. ; Atochina-Vasserman, E. N. ; Weissman, D . mRNA-based therapeutics: looking beyond COVID-19 vaccines . Lancet , 2024 , 403 ( 10432 ), 1192 – 1204 .

Yuan, Y. L. ; Jiao, B. H. ; Qu, L. L. ; Yang, D. M. ; Liu, R. J . The development of COVID-19 treatment . Front. Immunol. , 2023 , 14 , 1125246 .

Adu, P. ; Popoola, T. ; Medvedev, O. N. ; Collings, S. ; Mbinta, J. ; Aspin, C. ; Simpson, C. R . Implications for COVID-19 vaccine uptake: a systematic review . J. Infect. Public Health , 2023 , 16 ( 3 ), 441 – 466 .

Qiu, G. Y. ; Zhang, X. L. ; DeMello, A. J. ; Yao, M. S. ; Cao, J. J. ; Wang, J . On-site airborne pathogen detection for infection risk mitigation . Chem. Soc. Rev. , 2023 , 52 ( 24 ), 8531 – 8579 .

Sivakumar, R. ; Lee, N. Y . Recent advances in airborne pathogen detection using optical and electrochemical biosensors . Anal. Chim. Acta , 2022 , 1234 , 340297 .

Lan, S. ; Zhang, J. H. ; Li, J. ; Guo, Y. N. ; Sheng, X. L. ; Dong, A . An N -halamine/graphene oxide-functionalized electrospun polymer membrane that inactivates bacteria on contact and by releasing active chlorine . Polymers , 2021 , 13 ( 16 ), 2784 .

Chen, Z. ; Zhao, Q. H. ; Chen, J. H. ; Mei, T. ; Wang, W. W. ; Li, M. F. ; Wang, D . N -halamine-based polypropylene melt-blown nonwoven fabric with superhydrophilicity and antibacterial properties for face masks . Polymers , 2023 , 15 ( 21 ), 4335 .

Cerkez, I. ; Worley, S. D. ; Broughton, R. M. ; Huang, T. S . Antimicrobial surface coatings for polypropylene nonwoven fabrics . React. Funct. Polym. , 2013 , 73 ( 11 ), 1412 – 1419 .

Zhang, Y. P. ; Huang, P. ; Cheng, X. Q. ; Wang, R. M. ; He, Y. F. ; Song, P. F . Regulation of N -halamine copolymer morphology: transition from membrane to multiped nanospheres and antibacterial applications . Appl. Surf. Sci. , 2025 , 688 , 162425 .

Kong, Q. ; Li, Z. G. ; Ding, F. ; Ren, X. H . Hydrophobic N -halamine based POSS block copolymer porous films with antib acterial and resistance of bacterial adsorption performances . Chem. Eng. J. , 2021 , 410 , 128407 .

Wu, K. ; Hu, Y. L. ; Wu, X. L. ; Wang, S. L. ; Shang, M. Y. ; Yang, L. ; Sun, J. J . Fabrication of multifunctional cotton fabrics with quaternized N -halamine endowing the synergetic rechargeable antibacterial, wound healing and self-cleaning performances . Int. J. Biol. Macromol. , 2024 , 275 , 133493 .

Bromberg, L. ; Magariños, B. ; Concheiro, A. ; Hatton, T. A. ; Alvarez-Lorenzo, C . Nonleaching biocidal N -halamine-functionalized polyamine-, guanidine-, and hydantoi N -based coatings . Ind. Eng. Chem. Res. , 2024 , 63 ( 14 ), 6268 – 6278 .

Tian, M. W. ; Hu, X. L. ; Qu, L. J. ; Zhu, S. F. ; Sun, Y. N. ; Han, G. T . Versatile and ductile cotton fabric achieved via layer-by-layer self-assembly by consecutive adsorption of graphene doped PEDOT: PSS and chitosan . Carbon , 2016 , 96 , 1166 – 1174 .

Xue, T. ; Fang, D. J. ; Si, L. L. ; Yin, Y. J . Preparation of antibacterial and UV-protective cotton through coating with TiO 2 -modified chitosa N -based schiff bases . ACS Appl. Polym. Mater. , 2024 , 6 ( 14 ), 8073 – 8083 .

Jiang, L. ; Zhu, X. J. ; Li, J. Q. ; Shao, J. ; Zhang, Y. ; Zhu, J. T. ; Li, S. H. ; Zheng, L. N. ; Li, X. P. ; Zhang, S. H. ; Li, H. G. ; Zhong, G. J. ; Xu, H . Electroactive and breathable protective membranes by surface engineering of dielectric nanohybrids at poly(lactic acid) nanofibers with excellent self-sterilization and photothermal properties . Sep. Purif. Technol. , 2024 , 339 , 126708 .

Demir, B. ; Broughton, R. M. ; Huang, T. S. ; Bozack, M. J. ; Worley, S. D . Polymeric antimicrobial N -halamine-surface modification of stainless steel . Ind. Eng. Chem. Res. , 2017 , 56 ( 41 ), 11773 – 11781 .

Yan, S. J. ; Shi, H. C. ; Song, L. J. ; Wang, X. H. ; Liu, L. ; Luan, S. F. ; Yang, Y. M. ; Yin, J. H . Nonleaching bacteria-responsive antibacterial surface based on a unique hierarchical architecture . ACS Appl. Mater. Interfaces , 2016 , 8 ( 37 ), 24471 – 24481 .

Sun, X. B. ; Cao, Z. B. ; Porteous, N. ; Sun, Y. Y . Amine, melamine, and amide N -halamines as antimicrobial additives for polymers . Ind. Eng. Chem. Res. , 2010 , 49 ( 22 ), 11206 – 11213 .

Cerkez, I. ; Kocer, H. B. ; Worley, S. D. ; Broughton, R. M. ; Huang, T. S . N -halamine biocidal coatings via a layer-by-layer assembly technique . Langmuir , 2011 , 27 ( 7 ), 4091 – 4097 .

Zhang, X. Q. ; Lv, Q. ; Liu, S. ; Xu, T . Preparation and properties of recycled waste disposable medical protective clothing fragment modified asphalt . Constr. Build. Mater. , 2025 , 471 , 140738 .

Yang, J. J. ; Wang, J. H. ; Fan, C. H. ; Wu, Q. ; Yang, Y. ; Luo, D. ; Xiong, X. J. ; Fan, M. ; Ou, L . Effect of step potential on the structure and properties of ceramic coating on the surface of 2024 aluminum alloy thin sheets . Ceram. Int. , 2025 , 51 ( 2 ), 1392 – 1404 .

Oluomachi, E. ; Ahmed, A . Securing the future of healthcare: building a resilient defense system for patient data protection . Computer Science and Information Technology. , 2024 , 27 – 39 .

Porteous, N. ; Luo, J. ; Hererra, M. ; Schoolfield, J. ; Sun, Y. Y . Growth and identification of bacteria in N -halamine dental unit waterline tubing using an ultrapure water source . Int. J. Microbiol. , 2011 , 2011 ( 1 ), 767314 .

Xing, M. ; Zhang, H. F. ; Li, Z. Y. ; Zhang, L. ; Qian, W. H . Long-lasting renewable antibacterial N -halamine coating enable dental unit waterlines to prevention and control of contamination of dental treatment water . Front. Mater. , 2024 , 11 , 1399597 .

Zhou, Z. M. ; Liu, X. J. ; Mei, L. ; Guo, X. Q. ; Gao, Y. ; Hao, Y. P . Fabrication of N -halamine coatings with long-lasting bacterial inhibition and bacterial biofilm disruption functions for invisible aligner applications . Mater. Today Bio , 2025 , 33 , 102112 .

Liu, Y. H. ; Dong, T. ; Chen, Y. H. ; Sun, N. ; Liu, Q. ; Huang, Z. K. ; Yang, Y. F. ; Cheng, H. ; Yue, K . Biodegradable and cytocompatible hydrogel coating with antibacterial activity for the prevention of implant-associated infection . ACS Appl. Mater. Interfaces , 2023 , 15 ( 9 ), 11507 – 11519 .

Li, B. ; Liao, Y. ; Su, X. Y. ; Chen, S. Y. ; Wang, X. M. ; Shen, B. D. ; Song, H. ; Yue, P. F . Powering mesoporous silica nanoparticles into bioactive nanoplatforms for antibacterial therapies: Strategies and challenges . J. Nanobiotechnol. , 2023 , 21 ( 1 ), 325 .

Kristanti, R. A. ; Hadibarata, T. ; Syafrudin, M. ; Yılmaz, M. ; Abdullah, S . Microbiological contaminants in drinking water: current status and challenges . Water Air Soil Pollut. , 2022 , 233 ( 8 ), 299 .

Zheng, Y. X. ; Pan, N. Y. ; Liu, Y. ; Ren, X. H . Novel porous chitosan/ N -halamine structure with efficient antibacterial and hemostatic properties . Carbohydr. Polym. , 2021 , 253 , 117205 .

Ma, W. ; Li, L. ; Lin, X. H. ; Wang, Y. F. ; Ren, X. H. ; Huang, T. S . Novel ZnO/ N -halamine-mediated multifunctional dressings as quick antibacterial agent for biomedical applications . ACS Appl. Mater. Interfaces , 2019 , 11 ( 34 ), 31411 – 31420 .

Yin, M. L. ; Wang, Y. F. ; Zhang, Y. ; Ren, X. H. ; Qiu, Y. Y. ; Huang, T. S . Novel quaternarized N -halamine chitosan and polyvinyl alcohol nanofibrous membranes as hemostatic materials with excellent antibacterial properties . Carbohydr. Polym. , 2020 , 232 , 115823 .

Zhang, Y. D. ; Demir, B. ; Bertsch, G. ; Qiao, M. Y . Zwitterion and N -halamine functionalized cotton wound dressing with enhanced antifouling, antibacterial, and hemostatic properties . Int. J. Biol. Macromol. , 2023 , 230 , 123121 .

Hui, F. ; Debiemme-Chouvy, C . antimicrobial N -halamine polymers and coatings: a review of their synthesis, characterization, and applications . Biomacromolecules , 2013 , 14 ( 3 ), 585 – 601 .

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