最新刊期
      卷 19 ， 期 8 ， 2006
      • Hua-jie WANG,Xin-ming LIU,Jin-ye WANG
        Vol. 19, Issue 8, Pages: 1-9(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.001
        摘要：In this paper , the advance of natural macromolecules as the material for drug delivery microsphere carriers is summarized , and the classification of the materials , preparation and characterization of microspheres , the uses and administration of microspheres containing drug , and the existing problems are described in detail .  
        关键词：Natural macromolecule;Microspheres;Carrier;Control release   
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        发布时间：2022-09-18
      • Xiao-hua HE,Lian-dong DENG,An-jie DONG
        Vol. 19, Issue 8, Pages: 10-13,57(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.002
        摘要：As a kind of environmentally sensitive and controlled drug release systems,hydrogel nanoparticles have shown more and more potential application in the field of biomedicine. They were mainly used in the delivery of biomacromolecules such as polypeptide,protein etc. ,which have the properties as strong toxicity and side effect, short biological half-life time,easily degraded by bioenzyme. This review mainly summarizes the classification, preparation of hydrogel nanoparticles and their application in the field of biomedicine.  
        关键词：Hydrogel nanoparticles;Biomedicine;Environmentally sensitive;Temperature sensitive;pH sensitive   
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        发布时间：2022-09-18
      • Ping-ting XIONG,De-ping LU,Hong-zhi HUANG
        Vol. 19, Issue 8, Pages: 14-20,63(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.003
        摘要：Surfactants play a crucial role in the emulsion polymerization. However,they also have some adverse effects. A promising way to reduce the negative effects of the surfactants is to use polymerizable surfactants. Application of polymerizable surfactants ensures that the surfactant moiety is bound covalently to the polymer material so that desorption from the polymer particles or migration in the polymer film are impeded. This text concludes the characterization and properties of anionic,noionic,cationic polymerizable surfactants and their applications in emulsion polymerization.  
        关键词：Polymerizable;Surfactant;Anionic;Noionic;Cationic   
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        发布时间：2022-09-18
      • Jian-jie ZHAN,Zhao-hui CHEN,Yi PAN
        Vol. 19, Issue 8, Pages: 21-28(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.004
        摘要：The development of research on shape memory polymer,for major instance polyurethanes,were all reviewed. Genernal survey of studies,methods of synthesis,measures of characterization,mathematical models were introduced.  
        关键词：Shape memory;Polyurethane;Progress   
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        发布时间：2022-09-18
      • Xiao-dong ZHOU,Pei-hong NI
        Vol. 19, Issue 8, Pages: 29-38(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.005
        摘要：This review deals with recent progress in reversible addition-fragmentation chain transfer (RAFT) polymerization in heterogeneous phases, such as emulsion and miniemulsion systems .RAFT polymerization has been a versatile routine to synthesize a wide variety of functional monomers with controlled molecular weight and narrow MWD .Most of RAFT polymerizations have been achieved in bulk and solution systems .However, there are some issues of mass transfer and latex stability in RAFT/emulsion and RAFT/miniemulsion polymerization, leading to the failure of controlled molecular weight, the destabilization of colloidal polymers, and the formation of an intractable oily layer .The intrinsical reasons of these phenomena and improved methods have been proposed in literatures .The relationship between the mechanism of RAFT and the nucleation of latex particles in both emulsion and miniemulsion polymerization is also summarized in this article .  
        关键词：Emulsion;Miniemulsion;RAFT;Controlled/living free radical polymerization   
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        发布时间：2022-09-18
      • Hong-bing LI
        Vol. 19, Issue 8, Pages: 39-43,69(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.006
        摘要：The pharmacology of alginate and the practical usage of alginate as medicines,confirmed that alginate has better biocompliance. As well as its special physicochemical properties,such as forming gels with divalent cations under mild conditions,its services as delivery carrier for released coating,colon target system,microspheric embolus, nano-particle medicine,gene cure,ophthalmic drug delivery system,surgery recovering materials and transdermal therapeutic systems,increase the bioavailability of the drugs,and thus its therapeutic effect,reduce side effects, contribute to improve patient compliance. The article treats of the actuality of alginate product in china and expounds the promising perspective of alginate development.  
        关键词：Alginate;Biocompliance;Drug delivery carrier;Gel   
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        发布时间：2022-09-18
      • Yan-yan CUI,Jian-wen YANG,Zhao-hua ZENG,Yong-lie CHEN
        Vol. 19, Issue 8, Pages: 44-51(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.007
        摘要：The influences of monomer properties,reaction pressure,polymerization initiator and reaction vessel on frontal polymerization are reviewed. Both thermal and convective instabilities are discussed as well as strategies for their elimination. Photoinitiated frontal polymerization is also briefly introduced. The applications of frontal polymerization in manufacturing gradient materials,producing polyurethane,curing unsaturated polyester and epoxy resin,FROMP of dicyclopentadiene,forming IPNs structure and filling porous materials are reviewed herein.  
        关键词：Frontal polymerization;Convection;Photopolymerization;Stability;Gradient materials   
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        发布时间：2022-09-18
      • Lian-ying LIU,Yu-feng SUN,Chen-feng HE,Wan-tai YANG
        Vol. 19, Issue 8, Pages: 52-57(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.008
        摘要：Synthesizing microgels in solution is typically characterized with very low initial monomer concentration and quite incomplete conversion,which are disadvantageous to practice. In order to overcome these shortcomings, various attempts have been made in recent years. In this review,the latest investigations on the synthesis of microgels through polymerization of monomer or macromonomer in a concentrated solution, or cross-linking linear macromolecules directly in solution were overviewed and the research work need to be done in future was discussed.  
        关键词：Solution;Microgel;Synthesis   
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        发布时间：2022-09-18
      • Quan-kui LIN,Jian JI,Qing-gang TAN,Ke-feng REN,Jia-cong SHEN
        Vol. 19, Issue 8, Pages: 58-63(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.009
        摘要：The Layer-by-Layer self-assembly (LbL)of polycations and polyanions into multilayers has emerged as an efficient , versatile , yet simple , technique to create biologically active surfaces .By controlling the assemble condition , bioactive molecules , such as drugs , enzymes , DNA , or proteins , may be incorporated in the multilayer during the polyelecrolyte deposition process .The LbL technique has been recognized as an important means in designing the surfaces of the biomaterials .This paper summarized the progress on the Layer-by-Layer self-assemble technique in the design of the biointerface for cardiovascular device , tissue engineering scaffold , drug delivery systems , and so on .  
        关键词：Layer-by-Layer;Blood compatibility;Cell compatibility;Drug delivery;Antibacterial   
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        发布时间：2022-09-18
      • Xian-yong YUAN,Dong-xia HUO,Hong-ying WANG
        Vol. 19, Issue 8, Pages: 64-69(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.010
        摘要：With the development of the application of polymer latex,the study of film formation theory is attracting more attention. In this paper,film formation process of latex,forces operating on the latex particles during film formation and dynamics of film formations were introduced. In addition,characteristics and limitation of these theories were analyzed and the development trend in this field was also pointed out.  
        关键词：Latex;Film formation;Operative forces;Theory   
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        发布时间：2022-09-18
      • Yu-zhong NIU,Hou CHEN,Jian CHEN,Rong-jun QU
        Vol. 19, Issue 8, Pages: 70-78(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.011
        摘要：Living polymerization is one of the most active fields in polymer synthesis. Atom transfer radical polymerization (ATRP) has been widely used as an effective method for living polymerization of various kinds of monomers. ATRP is a simple process for controlled living radical polymerization leading to well-defined homopolymers and copolymers. In this article,the polymerization mechanism of ATRP was introduced,the application of atom transfer radical polymerization were summarized.  
        关键词：Atom transfer radical polymerization;Mechanism;Synthesis;Application   
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        发布时间：2022-09-18
      • Hai-e XU,Cui-e YAN
        Vol. 19, Issue 8, Pages: 79-87(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.012
        摘要：Gene vectors are of great importance in gene therapy .Non-viral gene vectors gain most attention as viral gene vectors have shown a series of safety problems during clinical application .Chitosan is one of the best potential non-viral gene vectors because of its excellent physico-chemical and biological properties .In recent years, a lot of works have been done on chitosan and its modification for gene delivery, and valuable progresses have been achieved .In this paper, recent progress in chitosan and its modification for gene delivery are reviewed in detail in terms of size, stability, specific targeting ability and transfection efficiency of chitosan/DNA complex for different cells .  
        关键词：Chitosan;DNA;Non-viral gene vectors;Modification;Progress   
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        发布时间：2022-09-18
      • Guo-jian WANG
        Vol. 19, Issue 8, Pages: 88-92(2006) DOI: 10.14028/j.cnki.1003-3726.2006.08.013
        摘要：In allusion to the some difficulties in the "polymer chemistry" course,such as the polymerization ability of propylene,the coefficient in the kinetics equation of termination for the radical polymerization,the deduction of equations of average polymerization degree from polymerization degree distribution functions,the definition of "mol coefficient" in the polycondensation reaction and the controlled/ "living" polymerization,the own comprehension and teaching realization were introduced.  
        关键词：Polymer chemistry;Difficulty;Teaching;Realization   
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        发布时间：2022-09-18
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