Ning LI, Yun-hui ZHANG, Xiao-li XIONG. Applications of Cyclodextrin Polymer in the Pharmic Research[J]. Polymer Bulletin, 2005,18(6):1-6. DOI: 10.14028/j.cnki.1003-3726.2005.06.001.
Cyclodextrin polymers (CDPs) not only have the inclusion ability
the controlled release ability
the catalysis ability and the selective ability
like their parent CDs
but also have fine mechanical intensity and the excellent stability.In addition
they exhibit various physical properties that have been impossible to obtain with their parent CDs.These lead CDPs to much attention.In this paper
progress in the preparation methods and the types of CDPs was summarized and application of CDPs in the enantiomer separation of chiral pharmaceuticals
improvement of the drug release
increase of the drug solubility
molecular imprinting technique and the drug delivery system was reviewed.
关键词
环糊精聚合物手性分离分子印迹聚合物药物释放给药系统
Keywords
Cyclodextrin polymers (CDPs)Enantiomer separationMolecular imprinted polymerDrug releaseDrug delivery system