Intelligent Hydrogels exhibit reversible swelling behavior in response to external stimulation

such as temperature

pH

solvent

ionic strength

electric field

magnetic field

light

pressure

specific analyte

etc. Improving the characteristic of intelligent hydrogels by molecular imprinting technique

those hydrogels not only have the ability of environmental responsiveness

but also have the specialty of molecular recognition. Hence

the molecularly imprinted intelligent hydrogels can auto-recognize and bind/release the specific analyte in respons to the external stimuli

which has potential application in delivery of drug

biosensors and immune analyse. In this paper

the development of molecularly imprinted intelligent hydrogels is reviewed. The challenges and the research tendency are discussed.