Based on the "lock-and-key" inclusion complexation between cyclodextrins and various guest molecules

which is strictly intermolekular non-covalent interaction

novel macromolecular networks can be formed. The novel networks have attracted much attention and have been the focus of macromolecular self-assembly in recent years due to the advantages of selectivity

regulating capability of cyclodextrins. In this paper

the recent progresses of macromolecular networks assembled by inclusive associations is reviewed

which mainly include: (1) supramolecular polymers

nanoparticles

association thickening fluid or supramolecular hydrogels induced by the complexation between cyclodextrin dimers

cyclodextrin crosslinked polymers

pendent cyclodextrin polymers

multi-arms star or hyperbranched polymers and the amphiphilic polymers; (2) hybrid organic-inorganic hydrogels prepared from CD-grafted new functional inorganic species and amphiphilic polymers; (3) the design and preparation of the supramolecular hydrogels with stimuli-responsive properties including pH

temperature

light

etc and their potential applications as drug / gene delivery carriers and tissue engineering scaffolds.