At present

most synthetic plastic materials produced from fossil carbon feedstock

which regenerated over time scales of millions of years. Petrochemical-derived plastic materials had been widely used

massive petro-plastic production consumed large amount energy resource and caused severe environmental pollution. Polyhydroxyalkanoates biosynthesized by microbe was macro polymer molecules

its physical and chemical characteristics were similar to conventional plastics such as polypropylene. Polyhydroxyalkanoates produced from renewable resource and have many advantages compared with petro-plastic

such as

it can be biodegraded in nature will not pollute environment

and the diverse structure endowed it with multiple function to feet for different use

which make polyhydroxyalkanoates extremely desirable substitutes for petro-plastic. Methane can be used as sole carbon and energy source for growth of methanotrophs. Methanotrophs can anabolism methane to accumulate polyhydroxyalkanoates in the cell at property conditions. Using methane as feedstock can substantially reducing cost for polyhydroxyalkanoates production

at the same time greatly reducing greenhouse gas emission. This article reviewed the fundamentals of strategies for reducing PHA production cost from methane and some explanation for methanotrophs

polyhydroxyalkanoates metabolic pathway

culture condition

and nutritional requirements are given.