Biomaterials are used in human tissues and organs to diagnosis diseases

repair and inprove body functions as high-tech materials. Extensive attention and comprehensive research have been done in the field of tissue engineering

regenerative medicine and drug delivery. However

the general existence of nonspecific protein absorption usually leads to the pollutions of the biomaterials and sometimes even life-threatening consequences. Therefore

the research of non-specific protein resistant materials has become a hot topic in the field of biomedical materials. Firstly

this paper intrdouces the process of protein absorption and the mechanism of anti-protein materials resistant materials. Then it foucuses on the public concerning anti-protein materials and their applications in the biomedical field. Finally

it shows a developing trend of biomaterials.