Traditional fossil plastics has brought a lot of convenience to human

but these refractory plastic are continuous accumulating in the environment

leading to the deterioration of global environment

the solid waste disposal problems. Therefore

the research and development of biodegradable plastic has become the main point in recent years. Polyhydroxyalkanoate (PHA)

a microbially synthesized polyesters with good biological degradability

biocompatibility and other special properties

can become the new biological materials alternative to traditional fossil plastic. Also PHA

as a heart valve tissue material

has achieved very good results in animal trials. It has shown good environmental effects and some promises. In this paper

the microorganisms in synthesis of PHA and their fermentation technology were reviewed combining with synthesis of PHA related research at home and abroad

then its development is prospected.