As a new hemostatic material

chitosan has been widely studied in recent years based on the characteristics of antibiosis

hemostasis

non-toxic

thromboplastin

biodegradation and biocompatibility. According to the defect of mechanical properties

hydrophobicity and slow hemostasis rate of chitosan

this paper review the research progress of chitosan with different cross-linking agents for increasing the mechanical properties

such as Jingniping

aldehydes and tannic acids. Furthermore

we also report the research progress of modification of chitosan for enhancing or decreasing solubility in water

such as carboxymethyl chitosan

chitosan quaternary ammonium salt and alkylated chitosan. Finally

we review chitosan composites by adding organic and inorganic materials for improving the hemostatic potential

including polyvinyl alcohol

gelatin and collagen.