Chun-bao MA, Chun-sheng KANG, Xu-bo YUAN, Jin CHANG. The Development of Biodegradable Drug Release Implants in Vivo[J]. Polymer Bulletin, 2005,18(6):65-69,75.
Chun-bao MA, Chun-sheng KANG, Xu-bo YUAN, Jin CHANG. The Development of Biodegradable Drug Release Implants in Vivo[J]. Polymer Bulletin, 2005,18(6):65-69,75. DOI: 10.14028/j.cnki.1003-3726.2005.06.011.
The implants were prepared by biodegradable polymers and drugs with physical packing or chemical connection ways.The drug in the polymer can diffuse from the channel of polymer with constant speed.It can affect only in the local site rather than in systemic tissues.The development of polymer matrix
preparation method
release mechanism of drug for biodegradable implants were also reviewed.