The preparation and characterization of the various NO-releasing polymeric materials are reviewed in this article.Although a large number of polymeric materials are currently employed to prepare various blood or tissue -contacting medical devices

the thrombogenic nature of such materials can cause serious complications in patients

and ultimately functional failure.Nitric oxide is a well-known anti-platelet agent that can inhibit the thrombosis. Hence

polymeric materials that can release NO locally may effectually solve the adverse problems of such materials.