金荣, 钟志远, Engbersen Johan F.J., 印杰. 基于碳水化合物的阳离子聚合物载体在基因释放中的应用[J]. 高分子通报, 2007,20(6):1-7.
Rong JIN, Zhi-yuan ZHONG, Johan F.J. Engbersen, Jie YIN. Carbohydrate-based Cationic Polymeric Vectors for Gene Delivery[J]. Polymer Bulletin, 2007,20(6):1-7.
Gene delivery system is indispensable for gene therapy .Recently
research on polymeric gene delivery vectors aims at developing non low cytotoxic cationic polymers for safe and efficient gene transfer .As a family of natural compounds
carbohydrate-based cationic polymer vectors are widely studied and applied to gene delivery due to their good biocompatibility and low cytotoxicity .This review describes the mechanism of polymeric gene delivery processes .Also
the latest typical carbohydrate-based polymers as non-viral vectors are reviewed .